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BDBM50131692 3,5-Dimethoxy-4'-amino-trans-stilbene::4-[2-(3,5-Dimethoxy-phenyl)-vinyl]-phenylamine::CHEMBL324290::trans-3,5-dimethoxyl-4'-aminostilbene

SMILES: COc1cc(OC)cc(\C=C\c2ccc(N)cc2)c1

InChI Key: InChIKey=LGVZJSLFOMGJOS-ONEGZZNKSA-N

Data: 2 IC50

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50131692   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 19A1


(Homo sapiens (Human))
BDBM50131692
PNG
(3,5-Dimethoxy-4'-amino-trans-stilbene | 4-[2-(3,5-...)
Show SMILES COc1cc(OC)cc(\C=C\c2ccc(N)cc2)c1
Show InChI InChI=1S/C16H17NO2/c1-18-15-9-13(10-16(11-15)19-2)4-3-12-5-7-14(17)8-6-12/h3-11H,17H2,1-2H3/b4-3+
PDB
MMDB

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PC cid
PC sid
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Article
PubMed
n/an/a 590n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of human aromatase preincubated with NADP+ for 10 mins before substrate addition measured after 30 mins


Bioorg Med Chem 18: 5352-66 (2010)


Article DOI: 10.1016/j.bmc.2010.05.042
BindingDB Entry DOI: 10.7270/Q2PK0H4P
More data for this
Ligand-Target Pair
Ribosyldihydronicotinamide dehydrogenase [quinone]


(Homo sapiens (Human))
BDBM50131692
PNG
(3,5-Dimethoxy-4'-amino-trans-stilbene | 4-[2-(3,5-...)
Show SMILES COc1cc(OC)cc(\C=C\c2ccc(N)cc2)c1
Show InChI InChI=1S/C16H17NO2/c1-18-15-9-13(10-16(11-15)19-2)4-3-12-5-7-14(17)8-6-12/h3-11H,17H2,1-2H3/b4-3+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
n/an/a 1.70E+3n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of human quinone reductase 2 expressed in Escherichia coli BL21(DE3) by UV-vis microplate reader analysis


Bioorg Med Chem 18: 5352-66 (2010)


Article DOI: 10.1016/j.bmc.2010.05.042
BindingDB Entry DOI: 10.7270/Q2PK0H4P
More data for this
Ligand-Target Pair