BDBM50131842 CHEMBL3633151

SMILES: COc1cc(ccc1Nc1ncc2c(C)cc(=O)n(-c3cccc(NC(=O)C=C)c3)c2n1)N(C)CCN(C)C

InChI Key: InChIKey=HWOFXAPUPWNIIO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50131842   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50131842 (CHEMBL3633151) Show SMILES COc1cc(ccc1Nc1ncc2c(C)cc(=O)n(-c3cccc(NC(=O)C=C)c3)c2n1)N(C)CCN(C)C Show InChI InChI=1S/C29H33N7O3/c1-7-26(37)31-20-9-8-10-22(16-20)36-27(38)15-19(2)23-18-30-29(33-28(23)36)32-24-12-11-21(17-25(24)39-6)35(5)14-13-34(3)4/h7-12,15-18H,1,13-14H2,2-6H3,(H,31,37)(H,30,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	521	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Binding affinity against delta opioid receptor in mouse hot plate test				ACS Med Chem Lett 6: 987-92 (2015) BindingDB Entry DOI: 10.7270/Q21C1ZPN
					More data for this Ligand-Target Pair