BDBM50131927 (2-Benzofuran-2-yl-oxazol-4-ylmethyl)-{2-[4-(2-methoxy-phenyl)-piperazin-1-yl]-ethyl}-amine::CHEMBL341117

SMILES: COc1ccccc1N1CCN(CCNCc2coc(n2)-c2cc3ccccc3o2)CC1

InChI Key: InChIKey=JCBILKVEETVNCO-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50131927   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50131927 ((2-Benzofuran-2-yl-oxazol-4-ylmethyl)-{2-[4-(2-met...) Show SMILES COc1ccccc1N1CCN(CCNCc2coc(n2)-c2cc3ccccc3o2)CC1 Show InChI InChI=1S/C25H28N4O3/c1-30-23-9-5-3-7-21(23)29-14-12-28(13-15-29)11-10-26-17-20-18-31-25(27-20)24-16-19-6-2-4-8-22(19)32-24/h2-9,16,18,26H,10-15,17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	518	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Binding affinity for rat striatum Dopamine receptor D2 by [3H]spiperone displacement.				J Med Chem 46: 3822-39 (2003) Article DOI: 10.1021/jm0211220 BindingDB Entry DOI: 10.7270/Q2H132RF
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM50131927 ((2-Benzofuran-2-yl-oxazol-4-ylmethyl)-{2-[4-(2-met...) Show SMILES COc1ccccc1N1CCN(CCNCc2coc(n2)-c2cc3ccccc3o2)CC1 Show InChI InChI=1S/C25H28N4O3/c1-30-23-9-5-3-7-21(23)29-14-12-28(13-15-29)11-10-26-17-20-18-31-25(27-20)24-16-19-6-2-4-8-22(19)32-24/h2-9,16,18,26H,10-15,17H2,1H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	759	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Binding affinity for rat striatum Dopamine receptor D3 (sf9 cells) by [3H]7-OH-DPAT displacement.				J Med Chem 46: 3822-39 (2003) Article DOI: 10.1021/jm0211220 BindingDB Entry DOI: 10.7270/Q2H132RF
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50131927 ((2-Benzofuran-2-yl-oxazol-4-ylmethyl)-{2-[4-(2-met...) Show SMILES COc1ccccc1N1CCN(CCNCc2coc(n2)-c2cc3ccccc3o2)CC1 Show InChI InChI=1S/C25H28N4O3/c1-30-23-9-5-3-7-21(23)29-14-12-28(13-15-29)11-10-26-17-20-18-31-25(27-20)24-16-19-6-2-4-8-22(19)32-24/h2-9,16,18,26H,10-15,17H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Binding affinity for rat striatum dopamine Dopamine receptor D1 by [3H]-SCH- -2339 displacement.				J Med Chem 46: 3822-39 (2003) Article DOI: 10.1021/jm0211220 BindingDB Entry DOI: 10.7270/Q2H132RF
					More data for this Ligand-Target Pair