BDBM50131936 Benzofuran-2-carboxylic acid {4-[4-(3,4-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide::CHEMBL125193

SMILES: Clc1ccc(cc1Cl)N1CCN(CCCCNC(=O)c2cc3ccccc3o2)CC1

InChI Key: InChIKey=IMEOUPAOCLGQOG-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50131936   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM50131936 (Benzofuran-2-carboxylic acid {4-[4-(3,4-dichloro-p...) Show SMILES Clc1ccc(cc1Cl)N1CCN(CCCCNC(=O)c2cc3ccccc3o2)CC1 Show InChI InChI=1S/C23H25Cl2N3O2/c24-19-8-7-18(16-20(19)25)28-13-11-27(12-14-28)10-4-3-9-26-23(29)22-15-17-5-1-2-6-21(17)30-22/h1-2,5-8,15-16H,3-4,9-14H2,(H,26,29)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Binding affinity for rat striatum Dopamine receptor D3 (sf9 cells) by [3H]7-OH-DPAT displacement.				J Med Chem 46: 3822-39 (2003) Article DOI: 10.1021/jm0211220 BindingDB Entry DOI: 10.7270/Q2H132RF
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50131936 (Benzofuran-2-carboxylic acid {4-[4-(3,4-dichloro-p...) Show SMILES Clc1ccc(cc1Cl)N1CCN(CCCCNC(=O)c2cc3ccccc3o2)CC1 Show InChI InChI=1S/C23H25Cl2N3O2/c24-19-8-7-18(16-20(19)25)28-13-11-27(12-14-28)10-4-3-9-26-23(29)22-15-17-5-1-2-6-21(17)30-22/h1-2,5-8,15-16H,3-4,9-14H2,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	333	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Binding affinity for rat striatum Dopamine receptor D2 by [3H]spiperone displacement.				J Med Chem 46: 3822-39 (2003) Article DOI: 10.1021/jm0211220 BindingDB Entry DOI: 10.7270/Q2H132RF
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50131936 (Benzofuran-2-carboxylic acid {4-[4-(3,4-dichloro-p...) Show SMILES Clc1ccc(cc1Cl)N1CCN(CCCCNC(=O)c2cc3ccccc3o2)CC1 Show InChI InChI=1S/C23H25Cl2N3O2/c24-19-8-7-18(16-20(19)25)28-13-11-27(12-14-28)10-4-3-9-26-23(29)22-15-17-5-1-2-6-21(17)30-22/h1-2,5-8,15-16H,3-4,9-14H2,(H,26,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.66E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Binding affinity for rat striatum dopamine Dopamine receptor D1 by [3H]-SCH- -2339 displacement.				J Med Chem 46: 3822-39 (2003) Article DOI: 10.1021/jm0211220 BindingDB Entry DOI: 10.7270/Q2H132RF
					More data for this Ligand-Target Pair