BDBM50131993 CHEMBL3633883

SMILES: C[C@H](NC(=O)CNC(=O)c1cccc(OC(F)(F)F)c1)c1ccccc1

InChI Key: InChIKey=OELFAMSGMBFKJT-LBPRGKRZSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50131993   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Probable G-protein coupled receptor 139 (Homo sapiens (Human))	BDBM50131993 (CHEMBL3633883) Show SMILES C[C@H](NC(=O)CNC(=O)c1cccc(OC(F)(F)F)c1)c1ccccc1 |r| Show InChI InChI=1S/C18H17F3N2O3/c1-12(13-6-3-2-4-7-13)23-16(24)11-22-17(25)14-8-5-9-15(10-14)26-18(19,20)21/h2-10,12H,11H2,1H3,(H,22,25)(H,23,24)/t12-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid UniChem Patents	PubMed	n/a	n/a	n/a	n/a	46	n/a	n/a	n/a	n/a
Janssen Research& Development, LLC Curated by ChEMBL					Assay Description Inhibition of [3H]-U-69,593 binding to Opioid receptor kappa 1				ACS Med Chem Lett 6: 1015-8 (2015) BindingDB Entry DOI: 10.7270/Q2RX9DWS
					More data for this Ligand-Target Pair