BDBM50132025 2-Oxo-2H-chromene-3-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide::CHEMBL126780::N-[4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl]-2-oxo-2H-1-benzopyran-3-carboxamide

SMILES: COc1ccccc1N1CCN(CCCCNC(=O)c2cc3ccccc3oc2=O)CC1

InChI Key: InChIKey=UCVFOYIRJYVIDW-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50132025   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50132025 (2-Oxo-2H-chromene-3-carboxylic acid {4-[4-(2-metho...) Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cc3ccccc3oc2=O)CC1 Show InChI InChI=1S/C25H29N3O4/c1-31-23-11-5-3-9-21(23)28-16-14-27(15-17-28)13-7-6-12-26-24(29)20-18-19-8-2-4-10-22(19)32-25(20)30/h2-5,8-11,18H,6-7,12-17H2,1H3,(H,26,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-Universität Curated by ChEMBL					Assay Description Binding affinity for human dopamine receptor D3 by displacing [125I]-iodosulpiride expressed in CHO cells				J Med Chem 46: 3883-99 (2003) Article DOI: 10.1021/jm030836n BindingDB Entry DOI: 10.7270/Q23F4P18
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50132025 (2-Oxo-2H-chromene-3-carboxylic acid {4-[4-(2-metho...) Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cc3ccccc3oc2=O)CC1 Show InChI InChI=1S/C25H29N3O4/c1-31-23-11-5-3-9-21(23)28-16-14-27(15-17-28)13-7-6-12-26-24(29)20-18-19-8-2-4-10-22(19)32-25(20)30/h2-5,8-11,18H,6-7,12-17H2,1H3,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-Universität Curated by ChEMBL					Assay Description Binding affinity for human dopamine receptor D2 by displacing [125I]-iodosulpiride expressed in CHO cells				J Med Chem 46: 3883-99 (2003) Article DOI: 10.1021/jm030836n BindingDB Entry DOI: 10.7270/Q23F4P18
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50132025 (2-Oxo-2H-chromene-3-carboxylic acid {4-[4-(2-metho...) Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cc3ccccc3oc2=O)CC1 Show InChI InChI=1S/C25H29N3O4/c1-31-23-11-5-3-9-21(23)28-16-14-27(15-17-28)13-7-6-12-26-24(29)20-18-19-8-2-4-10-22(19)32-25(20)30/h2-5,8-11,18H,6-7,12-17H2,1H3,(H,26,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	60.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Bari Curated by ChEMBL					Assay Description Displacement of [3H]spiroperidol from cloned human dopamine receptor D3 expressed in CHO cells				J Med Chem 49: 358-65 (2006) Article DOI: 10.1021/jm050734s BindingDB Entry DOI: 10.7270/Q2TX3F0W
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50132025 (2-Oxo-2H-chromene-3-carboxylic acid {4-[4-(2-metho...) Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cc3ccccc3oc2=O)CC1 Show InChI InChI=1S/C25H29N3O4/c1-31-23-11-5-3-9-21(23)28-16-14-27(15-17-28)13-7-6-12-26-24(29)20-18-19-8-2-4-10-22(19)32-25(20)30/h2-5,8-11,18H,6-7,12-17H2,1H3,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	146	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università degli Studi di Bari Curated by ChEMBL					Assay Description Displacement of [3H]spiroperidol from cloned human dopamine receptor D2(long) expressed in rat C6 glioma cells				J Med Chem 49: 358-65 (2006) Article DOI: 10.1021/jm050734s BindingDB Entry DOI: 10.7270/Q2TX3F0W
					More data for this Ligand-Target Pair