BDBM50132032 CHEMBL129035::N-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-3-[4-(2-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butylcarbamoyl}-vinyl)-phenyl]-acrylamide

SMILES: COc1ccccc1N1CCN(CCCCNC(=O)\C=C\c2ccc(\C=C\C(=O)NCCCCN3CCN(CC3)c3ccccc3OC)cc2)CC1

InChI Key: InChIKey=ICGNIALTNZWGJF-FLFKKZLDSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50132032   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50132032 (CHEMBL129035 | N-{4-[4-(2-Methoxy-phenyl)-piperazi...) Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)\C=C\c2ccc(\C=C\C(=O)NCCCCN3CCN(CC3)c3ccccc3OC)cc2)CC1 Show InChI InChI=1S/C42H56N6O4/c1-51-39-13-5-3-11-37(39)47-31-27-45(28-32-47)25-9-7-23-43-41(49)21-19-35-15-17-36(18-16-35)20-22-42(50)44-24-8-10-26-46-29-33-48(34-30-46)38-12-4-6-14-40(38)52-2/h3-6,11-22H,7-10,23-34H2,1-2H3,(H,43,49)(H,44,50)/b21-19+,22-20+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-Universität Curated by ChEMBL					Assay Description Binding affinity for human dopamine receptor D3 by displacing [125I]-iodosulpiride expressed in CHO cells				J Med Chem 46: 3883-99 (2003) Article DOI: 10.1021/jm030836n BindingDB Entry DOI: 10.7270/Q23F4P18
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50132032 (CHEMBL129035 | N-{4-[4-(2-Methoxy-phenyl)-piperazi...) Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)\C=C\c2ccc(\C=C\C(=O)NCCCCN3CCN(CC3)c3ccccc3OC)cc2)CC1 Show InChI InChI=1S/C42H56N6O4/c1-51-39-13-5-3-11-37(39)47-31-27-45(28-32-47)25-9-7-23-43-41(49)21-19-35-15-17-36(18-16-35)20-22-42(50)44-24-8-10-26-46-29-33-48(34-30-46)38-12-4-6-14-40(38)52-2/h3-6,11-22H,7-10,23-34H2,1-2H3,(H,43,49)(H,44,50)/b21-19+,22-20+	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-Universität Curated by ChEMBL					Assay Description Binding affinity for human dopamine receptor D2 by displacing [125I]-iodosulpiride expressed in CHO cells				J Med Chem 46: 3883-99 (2003) Article DOI: 10.1021/jm030836n BindingDB Entry DOI: 10.7270/Q23F4P18
					More data for this Ligand-Target Pair