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BDBM50132044 9-Oxo-9H-fluorene-4-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide::CHEMBL126834

SMILES: COc1ccccc1N1CCN(CCCCNC(=O)c2cccc3C(=O)c4ccccc4-c23)CC1

InChI Key: InChIKey=VUDZLQDQARJUEH-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50132044   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
D(3) dopamine receptor


(Homo sapiens (Human))
BDBM50132044
PNG
(9-Oxo-9H-fluorene-4-carboxylic acid {4-[4-(2-metho...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cccc3C(=O)c4ccccc4-c23)CC1
Show InChI InChI=1S/C29H31N3O3/c1-35-26-14-5-4-13-25(26)32-19-17-31(18-20-32)16-7-6-15-30-29(34)24-12-8-11-23-27(24)21-9-2-3-10-22(21)28(23)33/h2-5,8-14H,6-7,15-20H2,1H3,(H,30,34)
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
2.96n/an/an/an/an/an/an/an/a



Johann Wolfgang Goethe-Universität

Curated by ChEMBL


Assay Description
Binding affinity for human dopamine receptor D3 by displacing [125I]-iodosulpiride expressed in CHO cells


J Med Chem 46: 3883-99 (2003)


Article DOI: 10.1021/jm030836n
BindingDB Entry DOI: 10.7270/Q23F4P18
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50132044
PNG
(9-Oxo-9H-fluorene-4-carboxylic acid {4-[4-(2-metho...)
Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cccc3C(=O)c4ccccc4-c23)CC1
Show InChI InChI=1S/C29H31N3O3/c1-35-26-14-5-4-13-25(26)32-19-17-31(18-20-32)16-7-6-15-30-29(34)24-12-8-11-23-27(24)21-9-2-3-10-22(21)28(23)33/h2-5,8-14H,6-7,15-20H2,1H3,(H,30,34)
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
18n/an/an/an/an/an/an/an/a



Johann Wolfgang Goethe-Universität

Curated by ChEMBL


Assay Description
Binding affinity for human dopamine receptor D2 by displacing [125I]-iodosulpiride expressed in CHO cells


J Med Chem 46: 3883-99 (2003)


Article DOI: 10.1021/jm030836n
BindingDB Entry DOI: 10.7270/Q23F4P18
More data for this
Ligand-Target Pair