BDBM50132057 CHEMBL1180430::CHEMBL126128::N-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-3-phenyl-acrylamide; oxalic acid

SMILES: COc1ccccc1N1CCN(CCCCNC(=O)\C=C\c2ccccc2)CC1

InChI Key: InChIKey=HRXRYNFLHBSTFS-BUHFOSPRSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50132057   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50132057 (CHEMBL1180430 | CHEMBL126128 | N-{4-[4-(2-Methoxy-...) Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)\C=C\c2ccccc2)CC1 Show InChI InChI=1S/C24H31N3O2/c1-29-23-12-6-5-11-22(23)27-19-17-26(18-20-27)16-8-7-15-25-24(28)14-13-21-9-3-2-4-10-21/h2-6,9-14H,7-8,15-20H2,1H3,(H,25,28)/b14-13+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-Universität Curated by ChEMBL					Assay Description Binding affinity for human dopamine receptor D3 by displacing [125I]-iodosulpiride expressed in CHO cells				J Med Chem 46: 3883-99 (2003) Article DOI: 10.1021/jm030836n BindingDB Entry DOI: 10.7270/Q23F4P18
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50132057 (CHEMBL1180430 | CHEMBL126128 | N-{4-[4-(2-Methoxy-...) Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)\C=C\c2ccccc2)CC1 Show InChI InChI=1S/C24H31N3O2/c1-29-23-12-6-5-11-22(23)27-19-17-26(18-20-27)16-8-7-15-25-24(28)14-13-21-9-3-2-4-10-21/h2-6,9-14H,7-8,15-20H2,1H3,(H,25,28)/b14-13+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universität Erlangen-Nürnberg Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 6933-7 (2010) Article DOI: 10.1016/j.bmcl.2010.09.142 BindingDB Entry DOI: 10.7270/Q2474B38
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50132057 (CHEMBL1180430 | CHEMBL126128 | N-{4-[4-(2-Methoxy-...) Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)\C=C\c2ccccc2)CC1 Show InChI InChI=1S/C24H31N3O2/c1-29-23-12-6-5-11-22(23)27-19-17-26(18-20-27)16-8-7-15-25-24(28)14-13-21-9-3-2-4-10-21/h2-6,9-14H,7-8,15-20H2,1H3,(H,25,28)/b14-13+	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander-Universität Erlangen-Nürnberg Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2long receptor expressed in CHO cells				Bioorg Med Chem Lett 20: 6933-7 (2010) Article DOI: 10.1016/j.bmcl.2010.09.142 BindingDB Entry DOI: 10.7270/Q2474B38
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50132057 (CHEMBL1180430 | CHEMBL126128 | N-{4-[4-(2-Methoxy-...) Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)\C=C\c2ccccc2)CC1 Show InChI InChI=1S/C24H31N3O2/c1-29-23-12-6-5-11-22(23)27-19-17-26(18-20-27)16-8-7-15-25-24(28)14-13-21-9-3-2-4-10-21/h2-6,9-14H,7-8,15-20H2,1H3,(H,25,28)/b14-13+	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-Universität Curated by ChEMBL					Assay Description Binding affinity for human dopamine receptor D2 by displacing [125I]-iodosulpiride expressed in CHO cells				J Med Chem 46: 3883-99 (2003) Article DOI: 10.1021/jm030836n BindingDB Entry DOI: 10.7270/Q23F4P18
					More data for this Ligand-Target Pair