BDBM50132084 2-[3-(4-Fluoro-phenoxy)-propyl]-6-methoxy-5-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole::CHEMBL128184

SMILES: COc1cccc2c3CN(CCCOc4ccc(F)cc4)CCc3n(C)c12

InChI Key: InChIKey=HKDVQRRLOSMVKD-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50132084   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50132084 (2-[3-(4-Fluoro-phenoxy)-propyl]-6-methoxy-5-methyl...) Show SMILES COc1cccc2c3CN(CCCOc4ccc(F)cc4)CCc3n(C)c12 Show InChI InChI=1S/C22H25FN2O2/c1-24-20-11-13-25(12-4-14-27-17-9-7-16(23)8-10-17)15-19(20)18-5-3-6-21(26-2)22(18)24/h3,5-10H,4,11-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards rat 5-hydroxytryptamine 2A receptor expressed in NIH3T3 cells using [3H]ketanserin as radioligand				J Med Chem 46: 3930-7 (2003) Article DOI: 10.1021/jm030080s BindingDB Entry DOI: 10.7270/Q2V1245C
					More data for this Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat))	BDBM50132084 (2-[3-(4-Fluoro-phenoxy)-propyl]-6-methoxy-5-methyl...) Show SMILES COc1cccc2c3CN(CCCOc4ccc(F)cc4)CCc3n(C)c12 Show InChI InChI=1S/C22H25FN2O2/c1-24-20-11-13-25(12-4-14-27-17-9-7-16(23)8-10-17)15-19(20)18-5-3-6-21(26-2)22(18)24/h3,5-10H,4,11-15H2,1-2H3	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	225	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards rat 5-hydroxytryptamine 2C receptor expressed in A-9 cells using [3H]mesulergine as radioligand				J Med Chem 46: 3930-7 (2003) Article DOI: 10.1021/jm030080s BindingDB Entry DOI: 10.7270/Q2V1245C
					More data for this Ligand-Target Pair
5-HT5 (MOUSE)	BDBM50132084 (2-[3-(4-Fluoro-phenoxy)-propyl]-6-methoxy-5-methyl...) Show SMILES COc1cccc2c3CN(CCCOc4ccc(F)cc4)CCc3n(C)c12 Show InChI InChI=1S/C22H25FN2O2/c1-24-20-11-13-25(12-4-14-27-17-9-7-16(23)8-10-17)15-19(20)18-5-3-6-21(26-2)22(18)24/h3,5-10H,4,11-15H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.22E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards mouse 5-hydroxytryptamine 5A receptor using LSD as radioligand				J Med Chem 46: 3930-7 (2003) Article DOI: 10.1021/jm030080s BindingDB Entry DOI: 10.7270/Q2V1245C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 5A (Homo sapiens (Human))	BDBM50132084 (2-[3-(4-Fluoro-phenoxy)-propyl]-6-methoxy-5-methyl...) Show SMILES COc1cccc2c3CN(CCCOc4ccc(F)cc4)CCc3n(C)c12 Show InChI InChI=1S/C22H25FN2O2/c1-24-20-11-13-25(12-4-14-27-17-9-7-16(23)8-10-17)15-19(20)18-5-3-6-21(26-2)22(18)24/h3,5-10H,4,11-15H2,1-2H3	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 5A receptor using LSD as radioligand				J Med Chem 46: 3930-7 (2003) Article DOI: 10.1021/jm030080s BindingDB Entry DOI: 10.7270/Q2V1245C
					More data for this Ligand-Target Pair