BDBM50132105 4-[3-(5-Methyl-1,3,4,5-tetrahydro-pyrido[4,3-b]indol-2-yl)-propoxy]-phenylamine::CHEMBL435814

SMILES: Cn1c2CCN(CCCOc3ccc(N)cc3)Cc2c2ccccc12

InChI Key: InChIKey=QEOFCXKCKVVHLM-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50132105   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 5A (Homo sapiens (Human))	BDBM50132105 (4-[3-(5-Methyl-1,3,4,5-tetrahydro-pyrido[4,3-b]ind...) Show SMILES Cn1c2CCN(CCCOc3ccc(N)cc3)Cc2c2ccccc12 Show InChI InChI=1S/C21H25N3O/c1-23-20-6-3-2-5-18(20)19-15-24(13-11-21(19)23)12-4-14-25-17-9-7-16(22)8-10-17/h2-3,5-10H,4,11-15,22H2,1H3	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 5A receptor using LSD as radioligand				J Med Chem 46: 3930-7 (2003) Article DOI: 10.1021/jm030080s BindingDB Entry DOI: 10.7270/Q2V1245C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50132105 (4-[3-(5-Methyl-1,3,4,5-tetrahydro-pyrido[4,3-b]ind...) Show SMILES Cn1c2CCN(CCCOc3ccc(N)cc3)Cc2c2ccccc12 Show InChI InChI=1S/C21H25N3O/c1-23-20-6-3-2-5-18(20)19-15-24(13-11-21(19)23)12-4-14-25-17-9-7-16(22)8-10-17/h2-3,5-10H,4,11-15,22H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	285	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards rat 5-hydroxytryptamine 2A receptor expressed in NIH3T3 cells using [3H]ketanserin as radioligand				J Med Chem 46: 3930-7 (2003) Article DOI: 10.1021/jm030080s BindingDB Entry DOI: 10.7270/Q2V1245C
					More data for this Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat))	BDBM50132105 (4-[3-(5-Methyl-1,3,4,5-tetrahydro-pyrido[4,3-b]ind...) Show SMILES Cn1c2CCN(CCCOc3ccc(N)cc3)Cc2c2ccccc12 Show InChI InChI=1S/C21H25N3O/c1-23-20-6-3-2-5-18(20)19-15-24(13-11-21(19)23)12-4-14-25-17-9-7-16(22)8-10-17/h2-3,5-10H,4,11-15,22H2,1H3	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards rat 5-hydroxytryptamine 2C receptor expressed in A-9 cells using [3H]mesulergine as radioligand				J Med Chem 46: 3930-7 (2003) Article DOI: 10.1021/jm030080s BindingDB Entry DOI: 10.7270/Q2V1245C
					More data for this Ligand-Target Pair