BDBM50132121 8-Chloro-2-[3-(4-fluoro-phenoxy)-propyl]-5-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole::CHEMBL338095
SMILES: Cn1c2CCN(CCCOc3ccc(F)cc3)Cc2c2cc(Cl)ccc12
InChI Key: InChIKey=BCQBDOPTUDKMGI-UHFFFAOYSA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat)) | BDBM50132121 (8-Chloro-2-[3-(4-fluoro-phenoxy)-propyl]-5-methyl-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Binding affinity towards rat 5-hydroxytryptamine 2A receptor expressed in NIH3T3 cells using [3H]ketanserin as radioligand | J Med Chem 46: 3930-7 (2003) Article DOI: 10.1021/jm030080s BindingDB Entry DOI: 10.7270/Q2V1245C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-HT5 (MOUSE) | BDBM50132121 (8-Chloro-2-[3-(4-fluoro-phenoxy)-propyl]-5-methyl-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Binding affinity towards mouse 5-hydroxytryptamine 5A receptor using LSD as radioligand | J Med Chem 46: 3930-7 (2003) Article DOI: 10.1021/jm030080s BindingDB Entry DOI: 10.7270/Q2V1245C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 5A (Homo sapiens (Human)) | BDBM50132121 (8-Chloro-2-[3-(4-fluoro-phenoxy)-propyl]-5-methyl-...) | KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 270 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Binding affinity towards human 5-hydroxytryptamine 5A receptor using LSD as radioligand | J Med Chem 46: 3930-7 (2003) Article DOI: 10.1021/jm030080s BindingDB Entry DOI: 10.7270/Q2V1245C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat)) | BDBM50132121 (8-Chloro-2-[3-(4-fluoro-phenoxy)-propyl]-5-methyl-...) | KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Binding affinity towards rat 5-hydroxytryptamine 2C receptor expressed in A-9 cells using [3H]mesulergine as radioligand | J Med Chem 46: 3930-7 (2003) Article DOI: 10.1021/jm030080s BindingDB Entry DOI: 10.7270/Q2V1245C | |||||||||||
More data for this Ligand-Target Pair |