null

SMILES: OC(=O)c1n[nH]c2CCCc12

InChI Key: InChIKey=FCYBBDFUBSEGMX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50132140   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50132140 (1,4,5,6-Tetrahydro-cyclopentapyrazole-3-carboxylic...) Show SMILES OC(=O)c1n[nH]c2CCCc12 Show InChI InChI=1S/C7H8N2O2/c10-7(11)6-4-2-1-3-5(4)8-9-6/h1-3H2,(H,8,9)(H,10,11)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	156	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity at GPR109a				J Med Chem 51: 7653-62 (2008) Article DOI: 10.1021/jm800896z BindingDB Entry DOI: 10.7270/Q27D2TZ5
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Rattus norvegicus)	BDBM50132140 (1,4,5,6-Tetrahydro-cyclopentapyrazole-3-carboxylic...) Show SMILES OC(=O)c1n[nH]c2CCCc12 Show InChI InChI=1S/C7H8N2O2/c10-7(11)6-4-2-1-3-5(4)8-9-6/h1-3H2,(H,8,9)(H,10,11)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	156	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leiden/Amsterdam Center for Drug Research Curated by ChEMBL					Assay Description Inhibition of [3H]-nicotinic acid (20 nM) binding to nicotinic acid receptor in rat spleen membrane.				J Med Chem 46: 3945-51 (2003) Article DOI: 10.1021/jm030888c BindingDB Entry DOI: 10.7270/Q2V988TK
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50132140 (1,4,5,6-Tetrahydro-cyclopentapyrazole-3-carboxylic...) Show SMILES OC(=O)c1n[nH]c2CCCc12 Show InChI InChI=1S/C7H8N2O2/c10-7(11)6-4-2-1-3-5(4)8-9-6/h1-3H2,(H,8,9)(H,10,11)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.04E+4	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity against human GPR109a assessed as GTPgammaS binding				J Med Chem 51: 5101-8 (2008) Article DOI: 10.1021/jm800258p BindingDB Entry DOI: 10.7270/Q2CF9PWV
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50132140 (1,4,5,6-Tetrahydro-cyclopentapyrazole-3-carboxylic...) Show SMILES OC(=O)c1n[nH]c2CCCc12 Show InChI InChI=1S/C7H8N2O2/c10-7(11)6-4-2-1-3-5(4)8-9-6/h1-3H2,(H,8,9)(H,10,11)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	860	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity against human GPR109a assessed as forskolin-induced cAMP accumulation				J Med Chem 51: 5101-8 (2008) Article DOI: 10.1021/jm800258p BindingDB Entry DOI: 10.7270/Q2CF9PWV
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50132140 (1,4,5,6-Tetrahydro-cyclopentapyrazole-3-carboxylic...) Show SMILES OC(=O)c1n[nH]c2CCCc12 Show InChI InChI=1S/C7H8N2O2/c10-7(11)6-4-2-1-3-5(4)8-9-6/h1-3H2,(H,8,9)(H,10,11)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	860	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test				Bioorg Med Chem Lett 17: 4914-9 (2007) Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Mus musculus)	BDBM50132140 (1,4,5,6-Tetrahydro-cyclopentapyrazole-3-carboxylic...) Show SMILES OC(=O)c1n[nH]c2CCCc12 Show InChI InChI=1S/C7H8N2O2/c10-7(11)6-4-2-1-3-5(4)8-9-6/h1-3H2,(H,8,9)(H,10,11)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	500	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity against mouse GPR109a assessed as forskolin-induced cAMP accumulation				J Med Chem 51: 5101-8 (2008) Article DOI: 10.1021/jm800258p BindingDB Entry DOI: 10.7270/Q2CF9PWV
					More data for this Ligand-Target Pair