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BDBM50132142 4,5,6,7-Tetrahydro-1H-indazole-3-carboxylic acid::4,5,6,7-tetrahydro-2H-indazole-3-carboxylic acid::CHEMBL338405

SMILES: OC(=O)c1n[nH]c2CCCCc12

InChI Key: InChIKey=LWXNHFZBFJMHGU-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50132142   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Hydroxycarboxylic acid receptor 2


(Homo sapiens (Human))
BDBM50132142
PNG
(4,5,6,7-Tetrahydro-1H-indazole-3-carboxylic acid |...)
Show SMILES OC(=O)c1n[nH]c2CCCCc12
Show InChI InChI=1S/C8H10N2O2/c11-8(12)7-5-3-1-2-4-6(5)9-10-7/h1-4H2,(H,9,10)(H,11,12)
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Article
PubMed
3.50E+3n/an/an/an/an/an/an/an/a



Arena Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Binding affinity at GPR109a


J Med Chem 51: 7653-62 (2008)


Article DOI: 10.1021/jm800896z
More data for this
Ligand-Target Pair
Hydroxycarboxylic acid receptor 2


(Rattus norvegicus)
BDBM50132142
PNG
(4,5,6,7-Tetrahydro-1H-indazole-3-carboxylic acid |...)
Show SMILES OC(=O)c1n[nH]c2CCCCc12
Show InChI InChI=1S/C8H10N2O2/c11-8(12)7-5-3-1-2-4-6(5)9-10-7/h1-4H2,(H,9,10)(H,11,12)
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CHEMBL
PC cid
PC sid
UniChem

Patents

Article
PubMed
3.54E+3n/an/an/an/an/an/an/an/a



Leiden/Amsterdam Center for Drug Research

Curated by ChEMBL


Assay Description
Inhibition of [3H]-nicotinic acid (20 nM) binding to nicotinic acid receptor in rat spleen membrane.


J Med Chem 46: 3945-51 (2003)


Article DOI: 10.1021/jm030888c
More data for this
Ligand-Target Pair