BDBM50132192 CHEMBL102871::N*2*-(4-Amino-cyclohexyl)-N*6*-(3-chloro-phenyl)-9-isopropyl-9H-purine-2,6-diamine
SMILES: CC(C)n1cnc2c(Nc3cccc(Cl)c3)nc(NC3CCC(N)CC3)nc12
InChI Key: InChIKey=AUZUZIZPNYPPHU-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM50132192 (CHEMBL102871 | N*2*-(4-Amino-cyclohexyl)-N*6*-(3-c...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Academy of Sciences of the Czech Republic Curated by ChEMBL | Assay Description Inhibitory concentration against Cyclin dependent kinase 1. | Bioorg Med Chem Lett 13: 2993-6 (2003) BindingDB Entry DOI: 10.7270/Q270820N | |||||||||||
More data for this Ligand-Target Pair |