null

SMILES: COc1cc2nc(Cl)nc(N3CCN(CC3)C(=O)Nc3ccc(Oc4ccccc4)cc3)c2cc1OC

InChI Key: InChIKey=WIJBBZIFXNPQKP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50132203   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50132203 (4-(2-Chloro-6,7-dimethoxy-quinazolin-4-yl)-piperaz...) Show SMILES COc1cc2nc(Cl)nc(N3CCN(CC3)C(=O)Nc3ccc(Oc4ccccc4)cc3)c2cc1OC Show InChI InChI=1S/C27H26ClN5O4/c1-35-23-16-21-22(17-24(23)36-2)30-26(28)31-25(21)32-12-14-33(15-13-32)27(34)29-18-8-10-20(11-9-18)37-19-6-4-3-5-7-19/h3-11,16-17H,12-15H2,1-2H3,(H,29,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation was measured in intact cells using a two-site enzyme linked immunosorbent ...				J Med Chem 46: 4910-25 (2003) Article DOI: 10.1021/jm020505v BindingDB Entry DOI: 10.7270/Q2X929PJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50132203 (4-(2-Chloro-6,7-dimethoxy-quinazolin-4-yl)-piperaz...) Show SMILES COc1cc2nc(Cl)nc(N3CCN(CC3)C(=O)Nc3ccc(Oc4ccccc4)cc3)c2cc1OC Show InChI InChI=1S/C27H26ClN5O4/c1-35-23-16-21-22(17-24(23)36-2)30-26(28)31-25(21)32-12-14-33(15-13-32)27(34)29-18-8-10-20(11-9-18)37-19-6-4-3-5-7-19/h3-11,16-17H,12-15H2,1-2H3,(H,29,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>30	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibitory concentration against platelet-derived growth factor receptor beta phosphorylation in CHO cells				Bioorg Med Chem Lett 13: 3001-4 (2003) BindingDB Entry DOI: 10.7270/Q2668CKR
					More data for this Ligand-Target Pair