null

SMILES: COc1ccc2c(ncnc2c1OC)N1CCN(CC1)C(=O)Nc1ccc(Oc2ccccc2)cc1

InChI Key: InChIKey=PMSREEHLWBSKTF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50132204   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50132204 (4-(7,8-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...) Show SMILES COc1ccc2c(ncnc2c1OC)N1CCN(CC1)C(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C27H27N5O4/c1-34-23-13-12-22-24(25(23)35-2)28-18-29-26(22)31-14-16-32(17-15-31)27(33)30-19-8-10-21(11-9-19)36-20-6-4-3-5-7-20/h3-13,18H,14-17H2,1-2H3,(H,30,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation was measured in intact cells using a two-site enzyme linked immunosorbent ...				J Med Chem 46: 4910-25 (2003) Article DOI: 10.1021/jm020505v BindingDB Entry DOI: 10.7270/Q2X929PJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50132204 (4-(7,8-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...) Show SMILES COc1ccc2c(ncnc2c1OC)N1CCN(CC1)C(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C27H27N5O4/c1-34-23-13-12-22-24(25(23)35-2)28-18-29-26(22)31-14-16-32(17-15-31)27(33)30-19-8-10-21(11-9-19)36-20-6-4-3-5-7-20/h3-13,18H,14-17H2,1-2H3,(H,30,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>30	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibitory concentration against platelet-derived growth factor receptor beta phosphorylation in CHO cells				Bioorg Med Chem Lett 13: 3001-4 (2003) BindingDB Entry DOI: 10.7270/Q2668CKR
					More data for this Ligand-Target Pair