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BDBM50132210 4-(6-Amino-7-chloro-quinazolin-4-yl)-piperazine-1-carbothioic acid benzylamide::CHEMBL101227

SMILES: Nc1cc2c(ncnc2cc1Cl)N1CCN(CC1)C(=S)NCc1ccccc1

InChI Key: InChIKey=AVBJDAGBNFAPAJ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50132210   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM50132210
PNG
(4-(6-Amino-7-chloro-quinazolin-4-yl)-piperazine-1-...)
Show SMILES Nc1cc2c(ncnc2cc1Cl)N1CCN(CC1)C(=S)NCc1ccccc1
Show InChI InChI=1S/C20H21ClN6S/c21-16-11-18-15(10-17(16)22)19(25-13-24-18)26-6-8-27(9-7-26)20(28)23-12-14-4-2-1-3-5-14/h1-5,10-11,13H,6-9,12,22H2,(H,23,28)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 0.160n/an/an/an/an/an/a



Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL


Assay Description
Inhibitory concentration against platelet-derived growth factor receptor beta phosphorylation in CHO cells


Bioorg Med Chem Lett 13: 3001-4 (2003)


BindingDB Entry DOI: 10.7270/Q2668CKR
More data for this
Ligand-Target Pair