BDBM50132219 4-(6-Bromo-quinazolin-4-yl)-piperazine-1-carboxylic acid (4-phenoxy-phenyl)-amide::CHEMBL319255

SMILES: Brc1ccc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(Oc4ccccc4)cc3)c2c1

InChI Key: InChIKey=QOGQGIPYOFUJRK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50132219   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50132219 (4-(6-Bromo-quinazolin-4-yl)-piperazine-1-carboxyli...) Show SMILES Brc1ccc2ncnc(N3CCN(CC3)C(=O)Nc3ccc(Oc4ccccc4)cc3)c2c1 Show InChI InChI=1S/C25H22BrN5O2/c26-18-6-11-23-22(16-18)24(28-17-27-23)30-12-14-31(15-13-30)25(32)29-19-7-9-21(10-8-19)33-20-4-2-1-3-5-20/h1-11,16-17H,12-15H2,(H,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibitory concentration against platelet-derived growth factor receptor beta phosphorylation in CHO cells				Bioorg Med Chem Lett 13: 3001-4 (2003) BindingDB Entry DOI: 10.7270/Q2668CKR
					More data for this Ligand-Target Pair