BDBM50132235 4-Quinazolin-4-yl-piperazine-1-carbothioic acid benzylamide::CHEMBL103447

SMILES: S=C(NCc1ccccc1)N1CCN(CC1)c1ncnc2ccccc12

InChI Key: InChIKey=CJRLEEFSYTXKPA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50132235   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50132235 (4-Quinazolin-4-yl-piperazine-1-carbothioic acid be...) Show SMILES S=C(NCc1ccccc1)N1CCN(CC1)c1ncnc2ccccc12 Show InChI InChI=1S/C20H21N5S/c26-20(21-14-16-6-2-1-3-7-16)25-12-10-24(11-13-25)19-17-8-4-5-9-18(17)22-15-23-19/h1-9,15H,10-14H2,(H,21,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of platelet-derived growth factor receptor beta phosphorylation was measured in intact cells using a two-site enzyme linked immunosorbent ...				J Med Chem 46: 4910-25 (2003) Article DOI: 10.1021/jm020505v BindingDB Entry DOI: 10.7270/Q2X929PJ
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50132235 (4-Quinazolin-4-yl-piperazine-1-carbothioic acid be...) Show SMILES S=C(NCc1ccccc1)N1CCN(CC1)c1ncnc2ccccc12 Show InChI InChI=1S/C20H21N5S/c26-20(21-14-16-6-2-1-3-7-16)25-12-10-24(11-13-25)19-17-8-4-5-9-18(17)22-15-23-19/h1-9,15H,10-14H2,(H,21,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	>30	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibitory concentration against platelet-derived growth factor receptor beta phosphorylation in CHO cells				Bioorg Med Chem Lett 13: 3001-4 (2003) BindingDB Entry DOI: 10.7270/Q2668CKR
					More data for this Ligand-Target Pair