BindingDB PrimarySearch

BDBM50132341 CHEMBL3633757

SMILES: COc1cc2CCN(C)C3Cc4cc5OCOc5cc4-c(c1OCc1ccc(Br)cc1)c23

InChI Key: InChIKey=AJIMVLSQIMXLNV-UHFFFAOYSA-N

Data: 18 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50132341
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50132341 (CHEMBL3633757) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	<300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Binding affinity against alpha-1A adrenergic receptor				Bioorg Med Chem Lett 25: 5102-6 (2015) BindingDB Entry DOI: 10.7270/Q2HD7XGH
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM50132341 (CHEMBL3633757) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	<300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Inhibition of Mitogen-activated protein kinase p38 alpha				Bioorg Med Chem Lett 25: 5102-6 (2015) BindingDB Entry DOI: 10.7270/Q2HD7XGH
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50132341 (CHEMBL3633757) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	<300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Inhibition of Mitogen-activated protein kinase p38 alpha				Bioorg Med Chem Lett 25: 5102-6 (2015) BindingDB Entry DOI: 10.7270/Q2HD7XGH
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50132341 (CHEMBL3633757) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	<300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Binding affinity for prostanoid EP4 receptor				Bioorg Med Chem Lett 25: 5102-6 (2015) BindingDB Entry DOI: 10.7270/Q2HD7XGH
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50132341 (CHEMBL3633757) Show SMILES Show InChI	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	<300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Inhibition of Mitogen-activated protein kinase p38 alpha				Bioorg Med Chem Lett 25: 5102-6 (2015) BindingDB Entry DOI: 10.7270/Q2HD7XGH
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50132341 (CHEMBL3633757) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Binding affinity for 5-hydroxytryptamine 7 receptor				Bioorg Med Chem Lett 25: 5102-6 (2015) BindingDB Entry DOI: 10.7270/Q2HD7XGH
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50132341 (CHEMBL3633757) Show SMILES Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Binding affinity for 5-hydroxytryptamine 7 receptor				Bioorg Med Chem Lett 25: 5102-6 (2015) BindingDB Entry DOI: 10.7270/Q2HD7XGH
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50132341 (CHEMBL3633757) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Binding affinity for 5-hydroxytryptamine 7 receptor				Bioorg Med Chem Lett 25: 5102-6 (2015) BindingDB Entry DOI: 10.7270/Q2HD7XGH
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50132341 (CHEMBL3633757) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Binding affinity for 5-hydroxytryptamine 7 receptor				Bioorg Med Chem Lett 25: 5102-6 (2015) BindingDB Entry DOI: 10.7270/Q2HD7XGH
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H2 receptor (Homo sapiens (Human))	BDBM50132341 (CHEMBL3633757) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Inhibitory concentration of Bacillus stearothermophilus glucosidase (of family 13 alpha-glucosidase) at 1 umol/mL				Bioorg Med Chem Lett 25: 5102-6 (2015) BindingDB Entry DOI: 10.7270/Q2HD7XGH
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50132341 (CHEMBL3633757) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Competitive Inhibition constant for Bacillus stearothermophilus glucosidase				Bioorg Med Chem Lett 25: 5102-6 (2015) BindingDB Entry DOI: 10.7270/Q2HD7XGH
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Translocator protein (Homo sapiens (Human))	BDBM50132341 (CHEMBL3633757) Show SMILES Show InChI	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Binding affinity against alpha-1A adrenergic receptor				Bioorg Med Chem Lett 25: 5102-6 (2015) BindingDB Entry DOI: 10.7270/Q2HD7XGH
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50132341 (CHEMBL3633757) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Binding affinity for 5-hydroxytryptamine 7 receptor				Bioorg Med Chem Lett 25: 5102-6 (2015) BindingDB Entry DOI: 10.7270/Q2HD7XGH
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Homo sapiens (Human))	BDBM50132341 (CHEMBL3633757) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Binding affinity for 5-hydroxytryptamine 7 receptor				Bioorg Med Chem Lett 25: 5102-6 (2015) BindingDB Entry DOI: 10.7270/Q2HD7XGH
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50132341 (CHEMBL3633757) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Binding affinity for 5-hydroxytryptamine 7 receptor				Bioorg Med Chem Lett 25: 5102-6 (2015) BindingDB Entry DOI: 10.7270/Q2HD7XGH
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
Serotonin (5-HT) receptor (Homo sapiens (Human))	BDBM50132341 (CHEMBL3633757) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Binding affinity for 5-hydroxytryptamine 7 receptor				Bioorg Med Chem Lett 25: 5102-6 (2015) BindingDB Entry DOI: 10.7270/Q2HD7XGH
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50132341 (CHEMBL3633757) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Binding affinity for 5-hydroxytryptamine 7 receptor				Bioorg Med Chem Lett 25: 5102-6 (2015) BindingDB Entry DOI: 10.7270/Q2HD7XGH
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50132341 (CHEMBL3633757) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	>900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
City University of New York Curated by ChEMBL					Assay Description Binding affinity for 5-hydroxytryptamine 7 receptor				Bioorg Med Chem Lett 25: 5102-6 (2015) BindingDB Entry DOI: 10.7270/Q2HD7XGH
City University of New York Curated by ChEMBL					More data for this Ligand-Target Pair