BDBM50132355 2-(4-Chloro-phenyl)-6-morpholin-4-yl-pyran-4-one::2-(4-chlorophenyl)-6-morpholino-4H-pyran-4-one::CHEMBL105612

SMILES: Clc1ccc(cc1)-c1cc(=O)cc(o1)N1CCOCC1

InChI Key: InChIKey=VYDDKZSYMMZLQU-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50132355   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50132355 (2-(4-Chloro-phenyl)-6-morpholin-4-yl-pyran-4-one |...) Show SMILES Clc1ccc(cc1)-c1cc(=O)cc(o1)N1CCOCC1 Show InChI InChI=1S/C15H14ClNO3/c16-12-3-1-11(2-4-12)14-9-13(18)10-15(20-14)17-5-7-19-8-6-17/h1-4,9-10H,5-8H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
University of Newcastle Curated by ChEMBL					Assay Description In vitro inhibition of DNA-dependent protein kinase(DNA-PK) from HeLa (human carcinoma) cells.				Bioorg Med Chem Lett 13: 3083-6 (2003) BindingDB Entry DOI: 10.7270/Q2WS8SP4
					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50132355 (2-(4-Chloro-phenyl)-6-morpholin-4-yl-pyran-4-one |...) Show SMILES Clc1ccc(cc1)-c1cc(=O)cc(o1)N1CCOCC1 Show InChI InChI=1S/C15H14ClNO3/c16-12-3-1-11(2-4-12)14-9-13(18)10-15(20-14)17-5-7-19-8-6-17/h1-4,9-10H,5-8H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
University Hospital Hradec Kralove Curated by ChEMBL					Assay Description Inhibition of DNA-PK (unknown origin)				J Med Chem 58: 41-71 (2015) Article DOI: 10.1021/jm501026z BindingDB Entry DOI: 10.7270/Q2P84DJ7
					More data for this Ligand-Target Pair
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM50132355 (2-(4-Chloro-phenyl)-6-morpholin-4-yl-pyran-4-one |...) Show SMILES Clc1ccc(cc1)-c1cc(=O)cc(o1)N1CCOCC1 Show InChI InChI=1S/C15H14ClNO3/c16-12-3-1-11(2-4-12)14-9-13(18)10-15(20-14)17-5-7-19-8-6-17/h1-4,9-10H,5-8H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Newcastle University Curated by ChEMBL					Assay Description Inhibition of DNA-PK in HeLa cell nuclear extracts				J Med Chem 50: 1958-72 (2007) Article DOI: 10.1021/jm061121y BindingDB Entry DOI: 10.7270/Q2FB52MW
					More data for this Ligand-Target Pair