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BDBM50132404 4-(6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohexanecarboxylic acid amide::CHEMBL106878

SMILES: COc1cc2ncc(NC3CCC(CC3)C(N)=O)nc2cc1OC

InChI Key: InChIKey=HBZSOHZCCIMNIO-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50132404   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
PDGFR-beta/Platelet-derived growth factor receptor alpha


(Homo sapiens (Human))
BDBM50132404
PNG
(4-(6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohexane...)
Show SMILES COc1cc2ncc(NC3CCC(CC3)C(N)=O)nc2cc1OC |(-7.56,-1.47,;-7.56,.07,;-6.22,.84,;-4.89,.07,;-3.55,.84,;-2.23,.07,;-.88,.85,;-.88,2.4,;.44,3.18,;1.78,2.41,;3.1,3.19,;4.43,2.42,;4.43,.88,;3.1,.11,;1.78,.88,;5.76,.12,;5.77,-1.42,;7.1,.88,;-2.23,3.16,;-3.55,2.39,;-4.89,3.16,;-6.22,2.37,;-7.56,3.16,;-8.88,2.39,)|
Show InChI InChI=1S/C17H22N4O3/c1-23-14-7-12-13(8-15(14)24-2)21-16(9-19-12)20-11-5-3-10(4-6-11)17(18)22/h7-11H,3-6H2,1-2H3,(H2,18,22)(H,20,21)
PDB

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PC cid
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n/an/a 930n/an/an/an/an/an/a



Aventis Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of Platelet-derived growth factor receptor


Bioorg Med Chem Lett 13: 3097-100 (2003)


BindingDB Entry DOI: 10.7270/Q2HH6JGM
More data for this
Ligand-Target Pair