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BDBM50132406 4-(6,7-Dimethoxy-quinoxalin-2-ylamino)-2-methyl-cyclohexanol::CHEMBL104266

SMILES: COc1cc2ncc(N[C@@H]3CC[C@H](O)[C@@H](C)C3)nc2cc1OC

InChI Key: InChIKey=ZIKJGFZRXYVGMK-WDMOLILDSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50132406   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
PDGFR-beta/Platelet-derived growth factor receptor alpha


(Homo sapiens (Human))
BDBM50132406
PNG
(4-(6,7-Dimethoxy-quinoxalin-2-ylamino)-2-methyl-cy...)
Show SMILES COc1cc2ncc(N[C@@H]3CC[C@H](O)[C@@H](C)C3)nc2cc1OC
Show InChI InChI=1S/C17H23N3O3/c1-10-6-11(4-5-14(10)21)19-17-9-18-12-7-15(22-2)16(23-3)8-13(12)20-17/h7-11,14,21H,4-6H2,1-3H3,(H,19,20)/t10-,11+,14-/m0/s1
PDB

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n/an/a 18n/an/an/an/an/an/a



Aventis Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of Platelet-derived growth factor receptor


Bioorg Med Chem Lett 13: 3097-100 (2003)


BindingDB Entry DOI: 10.7270/Q2HH6JGM
More data for this
Ligand-Target Pair