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BDBM50132407 4-(6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohexanol::CHEMBL104074

SMILES: COc1cc2ncc(N[C@@H]3CC[C@H](O)CC3)nc2cc1OC

InChI Key: InChIKey=CYVRFHRDWQAJGA-PHIMTYICSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50132407   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
PDGFR-beta/Platelet-derived growth factor receptor alpha


(Homo sapiens (Human))
BDBM50132407
PNG
(4-(6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohexano...)
Show SMILES COc1cc2ncc(N[C@@H]3CC[C@H](O)CC3)nc2cc1OC |wD:9.8,12.12,(3.37,-6.65,;3.37,-5.12,;4.71,-4.35,;6.03,-5.12,;7.37,-4.35,;8.7,-5.12,;10.05,-4.33,;10.03,-2.79,;11.36,-2.01,;12.7,-2.78,;14.01,-2,;15.35,-2.77,;15.35,-4.31,;16.68,-5.07,;14.03,-5.08,;12.7,-4.31,;8.7,-2.03,;7.37,-2.8,;6.03,-2.03,;4.71,-2.81,;3.37,-2.03,;2.05,-2.8,)|
Show InChI InChI=1S/C16H21N3O3/c1-21-14-7-12-13(8-15(14)22-2)19-16(9-17-12)18-10-3-5-11(20)6-4-10/h7-11,20H,3-6H2,1-2H3,(H,18,19)/t10-,11+
PDB

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n/an/a 68n/an/an/an/an/an/a



Aventis Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of Platelet-derived growth factor receptor


Bioorg Med Chem Lett 13: 3097-100 (2003)


BindingDB Entry DOI: 10.7270/Q2HH6JGM
More data for this
Ligand-Target Pair