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BDBM50132408 4-(6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohexanecarboxylic acid methylamide::CHEMBL104581

SMILES: CNC(=O)C1CCC(CC1)Nc1cnc2cc(OC)c(OC)cc2n1

InChI Key: InChIKey=YCYBDORRCGUPOM-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50132408   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
PDGFR-beta/Platelet-derived growth factor receptor alpha


(Homo sapiens (Human))
BDBM50132408
PNG
(4-(6,7-Dimethoxy-quinoxalin-2-ylamino)-cyclohexane...)
Show SMILES CNC(=O)C1CCC(CC1)Nc1cnc2cc(OC)c(OC)cc2n1 |(7.11,-2.19,;5.77,-1.42,;5.76,.12,;7.1,.88,;4.43,.88,;4.43,2.42,;3.1,3.19,;1.78,2.41,;1.78,.88,;3.1,.11,;.44,3.18,;-.88,2.4,;-.88,.85,;-2.23,.07,;-3.55,.84,;-4.89,.07,;-6.22,.84,;-7.56,.07,;-7.56,-1.47,;-6.22,2.37,;-7.56,3.16,;-8.88,2.39,;-4.89,3.16,;-3.55,2.39,;-2.23,3.16,)|
Show InChI InChI=1S/C18H24N4O3/c1-19-18(23)11-4-6-12(7-5-11)21-17-10-20-13-8-15(24-2)16(25-3)9-14(13)22-17/h8-12H,4-7H2,1-3H3,(H,19,23)(H,21,22)
PDB

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PC cid
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PubMed
n/an/a 3.10E+3n/an/an/an/an/an/a



Aventis Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of Platelet-derived growth factor receptor


Bioorg Med Chem Lett 13: 3097-100 (2003)


BindingDB Entry DOI: 10.7270/Q2HH6JGM
More data for this
Ligand-Target Pair