BDBM50132419 5-Pyridin-3-yl-3-[1-(1H-pyrrol-2-yl)-meth-(Z)-ylidene]-1,3-dihydro-pyrrolo[3,2-b]pyridin-2-one::CHEMBL318390

SMILES: O=C1Nc2ccc(nc2\C1=C\c1ccc[nH]1)-c1cccnc1

InChI Key: InChIKey=AUUYHRKPCXZEOJ-LCYFTJDESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50132419   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Homo sapiens (Human))	BDBM50132419 (5-Pyridin-3-yl-3-[1-(1H-pyrrol-2-yl)-meth-(Z)-ylid...) Show SMILES O=C1Nc2ccc(nc2\C1=C\c1ccc[nH]1)-c1cccnc1 Show InChI InChI=1S/C17H12N4O/c22-17-13(9-12-4-2-8-19-12)16-15(21-17)6-5-14(20-16)11-3-1-7-18-10-11/h1-10,19H,(H,21,22)/b13-9-	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	235	n/a	n/a	n/a	n/a	n/a	n/a
Aventis Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against Janus Kinase 3 protein tyrosine kinase.				Bioorg Med Chem Lett 13: 3105-10 (2003) BindingDB Entry DOI: 10.7270/Q2833RDR
					More data for this Ligand-Target Pair