BDBM50132566 (4-Chloro-phenyl)-(5,7-dipropyl-3-trifluoromethyl-benzo[d]isoxazol-6-yloxy)-acetic acid::CHEMBL430894

SMILES: CCCc1cc2c(noc2c(CCC)c1OC(C(O)=O)c1ccc(Cl)cc1)C(F)(F)F

InChI Key: InChIKey=KWVHTJRFJCTACX-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50132566   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peroxisome proliferator-activated receptor alpha (PPAR alpha) (Homo sapiens (Human))	BDBM50132566 ((4-Chloro-phenyl)-(5,7-dipropyl-3-trifluoromethyl-...) Show SMILES CCCc1cc2c(noc2c(CCC)c1OC(C(O)=O)c1ccc(Cl)cc1)C(F)(F)F Show InChI InChI=1S/C22H21ClF3NO4/c1-3-5-13-11-16-19(31-27-20(16)22(24,25)26)15(6-4-2)17(13)30-18(21(28)29)12-7-9-14(23)10-8-12/h7-11,18H,3-6H2,1-2H3,(H,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards peroxisome proliferator activated receptor alpha (PPAR alpha)				Bioorg Med Chem Lett 13: 3185-90 (2003) BindingDB Entry DOI: 10.7270/Q2TQ6229
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50132566 ((4-Chloro-phenyl)-(5,7-dipropyl-3-trifluoromethyl-...) Show SMILES CCCc1cc2c(noc2c(CCC)c1OC(C(O)=O)c1ccc(Cl)cc1)C(F)(F)F Show InChI InChI=1S/C22H21ClF3NO4/c1-3-5-13-11-16-19(31-27-20(16)22(24,25)26)15(6-4-2)17(13)30-18(21(28)29)12-7-9-14(23)10-8-12/h7-11,18H,3-6H2,1-2H3,(H,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	105	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards peroxisome proliferator activated receptor alpha (PPAR alpha)				Bioorg Med Chem Lett 13: 3185-90 (2003) BindingDB Entry DOI: 10.7270/Q2TQ6229
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50132566 ((4-Chloro-phenyl)-(5,7-dipropyl-3-trifluoromethyl-...) Show SMILES CCCc1cc2c(noc2c(CCC)c1OC(C(O)=O)c1ccc(Cl)cc1)C(F)(F)F Show InChI InChI=1S/C22H21ClF3NO4/c1-3-5-13-11-16-19(31-27-20(16)22(24,25)26)15(6-4-2)17(13)30-18(21(28)29)12-7-9-14(23)10-8-12/h7-11,18H,3-6H2,1-2H3,(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards human peroxisome proliferator activated receptor alpha (PPAR alpha) was determined by HTRF assay				Bioorg Med Chem Lett 13: 3185-90 (2003) BindingDB Entry DOI: 10.7270/Q2TQ6229
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor (Homo sapiens (Human))	BDBM50132566 ((4-Chloro-phenyl)-(5,7-dipropyl-3-trifluoromethyl-...) Show SMILES CCCc1cc2c(noc2c(CCC)c1OC(C(O)=O)c1ccc(Cl)cc1)C(F)(F)F Show InChI InChI=1S/C22H21ClF3NO4/c1-3-5-13-11-16-19(31-27-20(16)22(24,25)26)15(6-4-2)17(13)30-18(21(28)29)12-7-9-14(23)10-8-12/h7-11,18H,3-6H2,1-2H3,(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	175	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity towards peroxisome proliferator activated receptor gamma (PPAR gamma)				Bioorg Med Chem Lett 13: 3185-90 (2003) BindingDB Entry DOI: 10.7270/Q2TQ6229
					More data for this Ligand-Target Pair