BDBM50132646 1-(4-Fluoro-benzyl)-4-(3-trifluoromethyl-phenyl)-piperidin-4-ol::CHEMBL109916

SMILES: OC1(CCN(Cc2ccc(F)cc2)CC1)c1cccc(c1)C(F)(F)F

InChI Key: InChIKey=DUUJPLJVPGJYKB-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50132646   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM50132646 (1-(4-Fluoro-benzyl)-4-(3-trifluoromethyl-phenyl)-p...) Show SMILES OC1(CCN(Cc2ccc(F)cc2)CC1)c1cccc(c1)C(F)(F)F Show InChI InChI=1S/C19H19F4NO/c20-17-6-4-14(5-7-17)13-24-10-8-18(25,9-11-24)15-2-1-3-16(12-15)19(21,22)23/h1-7,12,25H,8-11,13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	692	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. Curated by ChEMBL					Assay Description Binding affinity against human orphanin FQ receptor expressed in recombinant HEK 293 cells				Bioorg Med Chem Lett 13: 3247-52 (2003) BindingDB Entry DOI: 10.7270/Q2K936XQ
					More data for this Ligand-Target Pair