BDBM50132662 4-(4-Chloro-3-trifluoromethyl-phenyl)-1-naphthalen-2-ylmethyl-piperidin-4-ol::CHEMBL111233

SMILES: OC1(CCN(Cc2ccc3ccccc3c2)CC1)c1ccc(Cl)c(c1)C(F)(F)F

InChI Key: InChIKey=ZNWWFIQDEPGZND-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50132662   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50132662 (4-(4-Chloro-3-trifluoromethyl-phenyl)-1-naphthalen...) Show SMILES OC1(CCN(Cc2ccc3ccccc3c2)CC1)c1ccc(Cl)c(c1)C(F)(F)F Show InChI InChI=1S/C23H21ClF3NO/c24-21-8-7-19(14-20(21)23(25,26)27)22(29)9-11-28(12-10-22)15-16-5-6-17-3-1-2-4-18(17)13-16/h1-8,13-14,29H,9-12,15H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. Curated by ChEMBL					Assay Description Binding affinity for recombinant human mu-opioid receptor was determined by using [3H]- diprenophine radioligand				Bioorg Med Chem Lett 14: 5275-9 (2004) Article DOI: 10.1016/j.bmcl.2004.08.032 BindingDB Entry DOI: 10.7270/Q2K073RN
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50132662 (4-(4-Chloro-3-trifluoromethyl-phenyl)-1-naphthalen...) Show SMILES OC1(CCN(Cc2ccc3ccccc3c2)CC1)c1ccc(Cl)c(c1)C(F)(F)F Show InChI InChI=1S/C23H21ClF3NO/c24-21-8-7-19(14-20(21)23(25,26)27)22(29)9-11-28(12-10-22)15-16-5-6-17-3-1-2-4-18(17)13-16/h1-8,13-14,29H,9-12,15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	879	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. Curated by ChEMBL					Assay Description Binding affinity for opioid receptor like 1 expressed in HEK-293 cells				Bioorg Med Chem Lett 14: 5275-9 (2004) Article DOI: 10.1016/j.bmcl.2004.08.032 BindingDB Entry DOI: 10.7270/Q2K073RN
					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50132662 (4-(4-Chloro-3-trifluoromethyl-phenyl)-1-naphthalen...) Show SMILES OC1(CCN(Cc2ccc3ccccc3c2)CC1)c1ccc(Cl)c(c1)C(F)(F)F Show InChI InChI=1S/C23H21ClF3NO/c24-21-8-7-19(14-20(21)23(25,26)27)22(29)9-11-28(12-10-22)15-16-5-6-17-3-1-2-4-18(17)13-16/h1-8,13-14,29H,9-12,15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	879	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue Pharma L.P. Curated by ChEMBL					Assay Description Binding affinity against human orphanin FQ receptor expressed in recombinant HEK 293 cells				Bioorg Med Chem Lett 13: 3247-52 (2003) BindingDB Entry DOI: 10.7270/Q2K936XQ
					More data for this Ligand-Target Pair