BDBM50132810 CHEMBL3634452

SMILES: FC(F)(F)c1cc(Oc2ccc(CCOc3ccn4c(cnc4n3)-c3cncnc3)cc2)ccc1Cl

InChI Key: InChIKey=BZJPQXHEEVGVMK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50132810   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
LDL-associated phospholipase A2 (Homo sapiens (Human))	BDBM50132810 (CHEMBL3634452) Show SMILES FC(F)(F)c1cc(Oc2ccc(CCOc3ccn4c(cnc4n3)-c3cncnc3)cc2)ccc1Cl Show InChI InChI=1S/C25H17ClF3N5O2/c26-21-6-5-19(11-20(21)25(27,28)29)36-18-3-1-16(2-4-18)8-10-35-23-7-9-34-22(14-32-24(34)33-23)17-12-30-15-31-13-17/h1-7,9,11-15H,8,10H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant human Lp-PLA2 using 2-thio-PAF substrate after 10 mins				J Med Chem 58: 8529-41 (2015) BindingDB Entry DOI: 10.7270/Q2VQ34H4
					More data for this Ligand-Target Pair