BDBM50132811 CHEMBL3634454

SMILES: FC(F)(F)c1cc(Oc2ccc(COc3ccn4c(cnc4n3)-c3cncnc3)cc2)ccc1Cl

InChI Key: InChIKey=NUEDBDKXWAHMBH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50132811   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
LDL-associated phospholipase A2 (Homo sapiens (Human))	BDBM50132811 (CHEMBL3634454) Show SMILES FC(F)(F)c1cc(Oc2ccc(COc3ccn4c(cnc4n3)-c3cncnc3)cc2)ccc1Cl Show InChI InChI=1S/C24H15ClF3N5O2/c25-20-6-5-18(9-19(20)24(26,27)28)35-17-3-1-15(2-4-17)13-34-22-7-8-33-21(12-31-23(33)32-22)16-10-29-14-30-11-16/h1-12,14H,13H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant human Lp-PLA2 using 2-thio-PAF substrate after 10 mins				J Med Chem 58: 8529-41 (2015) BindingDB Entry DOI: 10.7270/Q2VQ34H4
					More data for this Ligand-Target Pair