BDBM50132817 CHEMBL3634550

SMILES: FC(F)(F)c1cc(Oc2ccc(COc3ccn4c(cnc4n3)-c3cncnc3)cc2C#N)ccc1Cl

InChI Key: InChIKey=AAVQOIXBVYVHJF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50132817   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
LDL-associated phospholipase A2 (Homo sapiens (Human))	BDBM50132817 (CHEMBL3634550) Show SMILES FC(F)(F)c1cc(Oc2ccc(COc3ccn4c(cnc4n3)-c3cncnc3)cc2C#N)ccc1Cl Show InChI InChI=1S/C25H14ClF3N6O2/c26-20-3-2-18(8-19(20)25(27,28)29)37-22-4-1-15(7-16(22)9-30)13-36-23-5-6-35-21(12-33-24(35)34-23)17-10-31-14-32-11-17/h1-8,10-12,14H,13H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant human Lp-PLA2 using 2-thio-PAF substrate after 10 mins				J Med Chem 58: 8529-41 (2015) BindingDB Entry DOI: 10.7270/Q2VQ34H4
					More data for this Ligand-Target Pair