BDBM50132819 CHEMBL3634555

SMILES: Fc1ccc(Oc2c(F)cc(COc3ccn4c(cnc4n3)-c3cncnc3)cc2F)cc1C(F)(F)F

InChI Key: InChIKey=PQBICOMBQYWZRR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50132819   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
LDL-associated phospholipase A2 (Homo sapiens (Human))	BDBM50132819 (CHEMBL3634555) Show SMILES Fc1ccc(Oc2c(F)cc(COc3ccn4c(cnc4n3)-c3cncnc3)cc2F)cc1C(F)(F)F Show InChI InChI=1S/C24H13F6N5O2/c25-17-2-1-15(7-16(17)24(28,29)30)37-22-18(26)5-13(6-19(22)27)11-36-21-3-4-35-20(10-33-23(35)34-21)14-8-31-12-32-9-14/h1-10,12H,11H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant human Lp-PLA2 using 2-thio-PAF substrate after 10 mins				J Med Chem 58: 8529-41 (2015) BindingDB Entry DOI: 10.7270/Q2VQ34H4
					More data for this Ligand-Target Pair