BDBM50132942 2-{[3-(2,4-Dichloro-phenyl)-1,5-dimethyl-1H-pyrazolo[4,3-b]pyridin-7-yl]-propyl-amino}-ethanol::CHEMBL332040

SMILES: CCCN(CCO)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl

InChI Key: InChIKey=OTOXJVRJQRHSJI-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50132942   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132942 (2-{[3-(2,4-Dichloro-phenyl)-1,5-dimethyl-1H-pyrazo...) Show SMILES CCCN(CCO)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C19H22Cl2N4O/c1-4-7-25(8-9-26)16-10-12(2)22-18-17(23-24(3)19(16)18)14-6-5-13(20)11-15(14)21/h5-6,10-11,26H,4,7-9H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards Corticotropin releasing factor receptor 1 was measured through displacement of [125I]-sauvagine expressed in HEK293 cells				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132942 (2-{[3-(2,4-Dichloro-phenyl)-1,5-dimethyl-1H-pyrazo...) Show SMILES CCCN(CCO)c1cc(C)nc2c(nn(C)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C19H22Cl2N4O/c1-4-7-25(8-9-26)16-10-12(2)22-18-17(23-24(3)19(16)18)14-6-5-13(20)11-15(14)21/h5-6,10-11,26H,4,7-9H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of (Corticotropin-Releasing Factor Receptor) CRF-stimulated cAMP production				Bioorg Med Chem Lett 13: 3371-4 (2003) BindingDB Entry DOI: 10.7270/Q21C1W8F
					More data for this Ligand-Target Pair