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BDBM50132962 CHEMBL115566::[8-(4-Chloro-phenyl)-7-methoxy-2-methyl-quinolin-4-yl]-dipropyl-amine

SMILES: CCCN(CCC)c1cc(C)nc2c(c(OC)ccc12)-c1ccc(Cl)cc1

InChI Key: InChIKey=SIIOIQCKIFYUAT-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50132962   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))		BDBM50132962
PNG
(CHEMBL115566 | [8-(4-Chloro-phenyl)-7-methoxy-2-me...)
Show SMILES CCCN(CCC)c1cc(C)nc2c(c(OC)ccc12)-c1ccc(Cl)cc1
Show InChI InChI=1S/C23H27ClN2O/c1-5-13-26(14-6-2)20-15-16(3)25-23-19(20)11-12-21(27-4)22(23)17-7-9-18(24)10-8-17/h7-12,15H,5-6,13-14H2,1-4H3
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PubMed
 9n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human Corticotropin releasing factor receptor 1 expressed in CHO cells using [125I]-o-CRF as the radioligand

Bioorg Med Chem Lett 13: 3375-9 (2003)


BindingDB Entry DOI: 10.7270/Q2WM1CS4
More data for this
Ligand-Target Pair