BDBM50133067 17,20-dioxa-4,12,14,23-tetraazahexacyclo[21.6.1.17,14.02,6.08,13.024,29]hentriaconta-1(30),2(6),7(31),8,10,12,24,26,28-nonaene-3,5-dione::CHEMBL334555

SMILES: O=C1NC(=O)C2=C1c1cn(CCOCCOCCn3cc2c2cccnc32)c2ccccc12

InChI Key: InChIKey=RZWOMXWGNHPLAV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50133067   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50133067 (17,20-dioxa-4,12,14,23-tetraazahexacyclo[21.6.1.17...) Show SMILES O=C1NC(=O)C2=C1c1cn(CCOCCOCCn3cc2c2cccnc32)c2ccccc12 |c:5| Show InChI InChI=1S/C25H22N4O4/c30-24-21-18-14-28(20-6-2-1-4-16(18)20)8-10-32-12-13-33-11-9-29-15-19(22(21)25(31)27-24)17-5-3-7-26-23(17)29/h1-7,14-15H,8-13H2,(H,27,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	138	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of Glycogen synthase kinase-3beta (GSK3-beta)				J Med Chem 46: 4021-31 (2003) Article DOI: 10.1021/jm030115o BindingDB Entry DOI: 10.7270/Q2G44R1D
					More data for this Ligand-Target Pair
Protein kinase C, gamma (Homo sapiens (Human))	BDBM50133067 (17,20-dioxa-4,12,14,23-tetraazahexacyclo[21.6.1.17...) Show SMILES O=C1NC(=O)C2=C1c1cn(CCOCCOCCn3cc2c2cccnc32)c2ccccc12 |c:5| Show InChI InChI=1S/C25H22N4O4/c30-24-21-18-14-28(20-6-2-1-4-16(18)20)8-10-32-12-13-33-11-9-29-15-19(22(21)25(31)27-24)17-5-3-7-26-23(17)29/h1-7,14-15H,8-13H2,(H,27,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of Protein kinase C gamma (PKC-gamma)				J Med Chem 46: 4021-31 (2003) Article DOI: 10.1021/jm030115o BindingDB Entry DOI: 10.7270/Q2G44R1D
					More data for this Ligand-Target Pair