BDBM50133126 5-[2-(3,5-Diisopropyl-2-propoxy-phenyl)-cyclopent-1-enyl]-3-methyl-penta-2,4-dienoic acid::CHEMBL133176

SMILES: CCCOc1c(cc(cc1C1=C(CCC1)\C=C\C(\C)=C\C(O)=O)C(C)C)C(C)C

InChI Key: InChIKey=AEXZEXFZLVOUCR-OTIKAVQOSA-N

Data: 8 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50133126   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NR2B Channel Blocker (RAT)	BDBM50133126 (5-[2-(3,5-Diisopropyl-2-propoxy-phenyl)-cyclopent-...) Show SMILES CCCOc1c(cc(cc1C1=C(CCC1)\C=C\C(\C)=C\C(O)=O)C(C)C)C(C)C |t:11| Show InChI InChI=1S/C26H36O3/c1-7-13-29-26-23(18(4)5)15-21(17(2)3)16-24(26)22-10-8-9-20(22)12-11-19(6)14-25(27)28/h11-12,14-18H,7-10,13H2,1-6H3,(H,27,28)/b12-11+,19-14+	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity for Retinoic acid receptor RXR-alpha was determined by competing with 3[H]-9-cis-RA				J Med Chem 46: 4087-103 (2003) Article DOI: 10.1021/jm020401k BindingDB Entry DOI: 10.7270/Q2VM4BNR
					More data for this Ligand-Target Pair
Retinoid X receptor gamma (Rattus norvegicus)	BDBM50133126 (5-[2-(3,5-Diisopropyl-2-propoxy-phenyl)-cyclopent-...) Show SMILES CCCOc1c(cc(cc1C1=C(CCC1)\C=C\C(\C)=C\C(O)=O)C(C)C)C(C)C |t:11| Show InChI InChI=1S/C26H36O3/c1-7-13-29-26-23(18(4)5)15-21(17(2)3)16-24(26)22-10-8-9-20(22)12-11-19(6)14-25(27)28/h11-12,14-18H,7-10,13H2,1-6H3,(H,27,28)/b12-11+,19-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity for Retinoic acid receptor RXR-gamma was determined by competing with 3[H]-9-cis-RA				J Med Chem 46: 4087-103 (2003) Article DOI: 10.1021/jm020401k BindingDB Entry DOI: 10.7270/Q2VM4BNR
					More data for this Ligand-Target Pair
Retinoid X receptor beta (Rattus norvegicus)	BDBM50133126 (5-[2-(3,5-Diisopropyl-2-propoxy-phenyl)-cyclopent-...) Show SMILES CCCOc1c(cc(cc1C1=C(CCC1)\C=C\C(\C)=C\C(O)=O)C(C)C)C(C)C |t:11| Show InChI InChI=1S/C26H36O3/c1-7-13-29-26-23(18(4)5)15-21(17(2)3)16-24(26)22-10-8-9-20(22)12-11-19(6)14-25(27)28/h11-12,14-18H,7-10,13H2,1-6H3,(H,27,28)/b12-11+,19-14+	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity for Retinoic acid receptor RXR-beta was determined by competing with 3[H]-9-cis-RA				J Med Chem 46: 4087-103 (2003) Article DOI: 10.1021/jm020401k BindingDB Entry DOI: 10.7270/Q2VM4BNR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor alpha (Rattus norvegicus)	BDBM50133126 (5-[2-(3,5-Diisopropyl-2-propoxy-phenyl)-cyclopent-...) Show SMILES CCCOc1c(cc(cc1C1=C(CCC1)\C=C\C(\C)=C\C(O)=O)C(C)C)C(C)C |t:11| Show InChI InChI=1S/C26H36O3/c1-7-13-29-26-23(18(4)5)15-21(17(2)3)16-24(26)22-10-8-9-20(22)12-11-19(6)14-25(27)28/h11-12,14-18H,7-10,13H2,1-6H3,(H,27,28)/b12-11+,19-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity for peroxisome Peroxisome proliferator activated receptor alpha was determined				J Med Chem 46: 4087-103 (2003) Article DOI: 10.1021/jm020401k BindingDB Entry DOI: 10.7270/Q2VM4BNR
					More data for this Ligand-Target Pair
Retinoic acid receptor gamma (Rattus norvegicus)	BDBM50133126 (5-[2-(3,5-Diisopropyl-2-propoxy-phenyl)-cyclopent-...) Show SMILES CCCOc1c(cc(cc1C1=C(CCC1)\C=C\C(\C)=C\C(O)=O)C(C)C)C(C)C |t:11| Show InChI InChI=1S/C26H36O3/c1-7-13-29-26-23(18(4)5)15-21(17(2)3)16-24(26)22-10-8-9-20(22)12-11-19(6)14-25(27)28/h11-12,14-18H,7-10,13H2,1-6H3,(H,27,28)/b12-11+,19-14+	PDB MMDB Reactome pathway UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity for Retinoic acid receptor gamma was determined by competing with 3[H]-ATRA				J Med Chem 46: 4087-103 (2003) Article DOI: 10.1021/jm020401k BindingDB Entry DOI: 10.7270/Q2VM4BNR
					More data for this Ligand-Target Pair
Retinoic acid receptor alpha (Rattus norvegicus)	BDBM50133126 (5-[2-(3,5-Diisopropyl-2-propoxy-phenyl)-cyclopent-...) Show SMILES CCCOc1c(cc(cc1C1=C(CCC1)\C=C\C(\C)=C\C(O)=O)C(C)C)C(C)C |t:11| Show InChI InChI=1S/C26H36O3/c1-7-13-29-26-23(18(4)5)15-21(17(2)3)16-24(26)22-10-8-9-20(22)12-11-19(6)14-25(27)28/h11-12,14-18H,7-10,13H2,1-6H3,(H,27,28)/b12-11+,19-14+	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity for Retinoic acid receptor alpha was determined by competing with 3[H]-ATRA				J Med Chem 46: 4087-103 (2003) Article DOI: 10.1021/jm020401k BindingDB Entry DOI: 10.7270/Q2VM4BNR
					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Rattus norvegicus)	BDBM50133126 (5-[2-(3,5-Diisopropyl-2-propoxy-phenyl)-cyclopent-...) Show SMILES CCCOc1c(cc(cc1C1=C(CCC1)\C=C\C(\C)=C\C(O)=O)C(C)C)C(C)C |t:11| Show InChI InChI=1S/C26H36O3/c1-7-13-29-26-23(18(4)5)15-21(17(2)3)16-24(26)22-10-8-9-20(22)12-11-19(6)14-25(27)28/h11-12,14-18H,7-10,13H2,1-6H3,(H,27,28)/b12-11+,19-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.22E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity for peroxisome proliferator activated receptor gamma				J Med Chem 46: 4087-103 (2003) Article DOI: 10.1021/jm020401k BindingDB Entry DOI: 10.7270/Q2VM4BNR
					More data for this Ligand-Target Pair
Retinoid receptor (Homo sapiens (Human))	BDBM50133126 (5-[2-(3,5-Diisopropyl-2-propoxy-phenyl)-cyclopent-...) Show SMILES CCCOc1c(cc(cc1C1=C(CCC1)\C=C\C(\C)=C\C(O)=O)C(C)C)C(C)C |t:11| Show InChI InChI=1S/C26H36O3/c1-7-13-29-26-23(18(4)5)15-21(17(2)3)16-24(26)22-10-8-9-20(22)12-11-19(6)14-25(27)28/h11-12,14-18H,7-10,13H2,1-6H3,(H,27,28)/b12-11+,19-14+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	5.62E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity for Retinoic acid receptor beta was determined by competing with 3[H]-ATRA				J Med Chem 46: 4087-103 (2003) Article DOI: 10.1021/jm020401k BindingDB Entry DOI: 10.7270/Q2VM4BNR
					More data for this Ligand-Target Pair
Retinoid X receptor alpha (RAT)	BDBM50133126 (5-[2-(3,5-Diisopropyl-2-propoxy-phenyl)-cyclopent-...) Show SMILES CCCOc1c(cc(cc1C1=C(CCC1)\C=C\C(\C)=C\C(O)=O)C(C)C)C(C)C |t:11| Show InChI InChI=1S/C26H36O3/c1-7-13-29-26-23(18(4)5)15-21(17(2)3)16-24(26)22-10-8-9-20(22)12-11-19(6)14-25(27)28/h11-12,14-18H,7-10,13H2,1-6H3,(H,27,28)/b12-11+,19-14+	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytes				J Med Chem 46: 4087-103 (2003) Article DOI: 10.1021/jm020401k BindingDB Entry DOI: 10.7270/Q2VM4BNR
					More data for this Ligand-Target Pair