BDBM50133138 9-Fluoro-5-[1-(2-isopropyl-phenyl)-meth-(Z)-ylidene]-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene::CHEMBL132672

SMILES: CC(C)c1ccccc1\C=C1/Oc2ccc(F)cc2-c2ccc3NC(C)(C)C=C(C)c3c12

InChI Key: InChIKey=QXUJGHLIYHYUAH-WGARJPEWSA-N

Data: 1 KI  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50133138   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50133138 (9-Fluoro-5-[1-(2-isopropyl-phenyl)-meth-(Z)-yliden...) Show SMILES CC(C)c1ccccc1\C=C1/Oc2ccc(F)cc2-c2ccc3NC(C)(C)C=C(C)c3c12 |t:29| Show InChI InChI=1S/C29H28FNO/c1-17(2)21-9-7-6-8-19(21)14-26-28-22(23-15-20(30)10-13-25(23)32-26)11-12-24-27(28)18(3)16-29(4,5)31-24/h6-17,31H,1-5H3/b26-14-	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity towards human progesterone receptor A isoform using progesterone as radioligand				J Med Chem 46: 4104-12 (2003) Article DOI: 10.1021/jm020477g BindingDB Entry DOI: 10.7270/Q2QZ29C6
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50133138 (9-Fluoro-5-[1-(2-isopropyl-phenyl)-meth-(Z)-yliden...) Show SMILES CC(C)c1ccccc1\C=C1/Oc2ccc(F)cc2-c2ccc3NC(C)(C)C=C(C)c3c12 |t:29| Show InChI InChI=1S/C29H28FNO/c1-17(2)21-9-7-6-8-19(21)14-26-28-22(23-15-20(30)10-13-25(23)32-26)11-12-24-27(28)18(3)16-29(4,5)31-24/h6-17,31H,1-5H3/b26-14-	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Agonistic activity against human progesterone receptor in CV-1 cells				J Med Chem 46: 4104-12 (2003) Article DOI: 10.1021/jm020477g BindingDB Entry DOI: 10.7270/Q2QZ29C6
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50133138 (9-Fluoro-5-[1-(2-isopropyl-phenyl)-meth-(Z)-yliden...) Show SMILES CC(C)c1ccccc1\C=C1/Oc2ccc(F)cc2-c2ccc3NC(C)(C)C=C(C)c3c12 |t:29| Show InChI InChI=1S/C29H28FNO/c1-17(2)21-9-7-6-8-19(21)14-26-28-22(23-15-20(30)10-13-25(23)32-26)11-12-24-27(28)18(3)16-29(4,5)31-24/h6-17,31H,1-5H3/b26-14-	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	54	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Agonistic activity against human progesterone receptor in T47D breast cancer cells				J Med Chem 46: 4104-12 (2003) Article DOI: 10.1021/jm020477g BindingDB Entry DOI: 10.7270/Q2QZ29C6
					More data for this Ligand-Target Pair