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SMILES: Fc1ccc2c(noc2c1)C1CCN(CCCOc2ccc(CCc3nc4ccccc4o3)cc2)CC1

InChI Key: InChIKey=JZZWBHDXYLOBGC-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50133174   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50133174 (CHEMBL3634824) Show SMILES Fc1ccc2c(noc2c1)C1CCN(CCCOc2ccc(CCc3nc4ccccc4o3)cc2)CC1 Show InChI InChI=1S/C30H30FN3O3/c31-23-9-12-25-28(20-23)37-33-30(25)22-14-17-34(18-15-22)16-3-19-35-24-10-6-21(7-11-24)8-13-29-32-26-4-1-2-5-27(26)36-29/h1-2,4-7,9-12,20,22H,3,8,13-19H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Huazhong University of Science and Technology Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from 5-HT1A receptor in rat cerebral cortex homogenates after 60 mins by liquid scintillation counting				Bioorg Med Chem Lett 25: 5299-305 (2015) BindingDB Entry DOI: 10.7270/Q26W9CW2
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50133174 (CHEMBL3634824) Show SMILES Fc1ccc2c(noc2c1)C1CCN(CCCOc2ccc(CCc3nc4ccccc4o3)cc2)CC1 Show InChI InChI=1S/C30H30FN3O3/c31-23-9-12-25-28(20-23)37-33-30(25)22-14-17-34(18-15-22)16-3-19-35-24-10-6-21(7-11-24)8-13-29-32-26-4-1-2-5-27(26)36-29/h1-2,4-7,9-12,20,22H,3,8,13-19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Huazhong University of Science and Technology Curated by ChEMBL					Assay Description Displacement of [3H]ketanserine from 5-HT2A receptor in rat cerebral cortex homogenates after 60 mins by liquid scintillation counting				Bioorg Med Chem Lett 25: 5299-305 (2015) BindingDB Entry DOI: 10.7270/Q26W9CW2
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50133174 (CHEMBL3634824) Show SMILES Fc1ccc2c(noc2c1)C1CCN(CCCOc2ccc(CCc3nc4ccccc4o3)cc2)CC1 Show InChI InChI=1S/C30H30FN3O3/c31-23-9-12-25-28(20-23)37-33-30(25)22-14-17-34(18-15-22)16-3-19-35-24-10-6-21(7-11-24)8-13-29-32-26-4-1-2-5-27(26)36-29/h1-2,4-7,9-12,20,22H,3,8,13-19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Huazhong University of Science and Technology Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from dopaminergic D2 receptor in rat striatum homogenates after 60 mins by liquid scintillation counting				Bioorg Med Chem Lett 25: 5299-305 (2015) BindingDB Entry DOI: 10.7270/Q26W9CW2
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50133174 (CHEMBL3634824) Show SMILES Fc1ccc2c(noc2c1)C1CCN(CCCOc2ccc(CCc3nc4ccccc4o3)cc2)CC1 Show InChI InChI=1S/C30H30FN3O3/c31-23-9-12-25-28(20-23)37-33-30(25)22-14-17-34(18-15-22)16-3-19-35-24-10-6-21(7-11-24)8-13-29-32-26-4-1-2-5-27(26)36-29/h1-2,4-7,9-12,20,22H,3,8,13-19H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
Huazhong University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of human ERG expressed in HEK293 cells by whole-cell patch clamp method				Bioorg Med Chem Lett 25: 5299-305 (2015) BindingDB Entry DOI: 10.7270/Q26W9CW2
					More data for this Ligand-Target Pair