BDBM50133339 CHEMBL3635002

SMILES: O=C1C=C(NC2CCN(Cc3ccccc3)CC2)c2ccccc2C1=O

InChI Key: InChIKey=HAJDDHBUKKLEIK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50133339   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human))	BDBM50133339 (CHEMBL3635002) Show SMILES O=C1C=C(NC2CCN(Cc3ccccc3)CC2)c2ccccc2C1=O |t:2| Show InChI InChI=1S/C22H22N2O2/c25-21-14-20(18-8-4-5-9-19(18)22(21)26)23-17-10-12-24(13-11-17)15-16-6-2-1-3-7-16/h1-9,14,17,23H,10-13,15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	5.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Basic Science (IBS) Curated by ChEMBL					Assay Description Inhibition of MALT1 in human Jurkat cell lysate preincubated for 2 hrs followed by addition of 25 uM Ac-LRSR-AMC substrate for 3 hrs by fluorescence ...				J Med Chem 58: 8491-502 (2015) BindingDB Entry DOI: 10.7270/Q2PZ5BN1
					More data for this Ligand-Target Pair