BDBM50133350 8-methoxy-beta-lapachone::CHEMBL2036880

SMILES: COc1ccc2C3=C(CCC(C)(C)O3)C(=O)C(=O)c2c1

InChI Key: InChIKey=OFUVMXZHDYXMJK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50133350   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human))	BDBM50133350 (8-methoxy-beta-lapachone | CHEMBL2036880) Show SMILES COc1ccc2C3=C(CCC(C)(C)O3)C(=O)C(=O)c2c1 |t:6| Show InChI InChI=1S/C16H16O4/c1-16(2)7-6-11-13(17)14(18)12-8-9(19-3)4-5-10(12)15(11)20-16/h4-5,8H,6-7H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Basic Science (IBS) Curated by ChEMBL					Assay Description Inhibition of His-tagged human MALT1 (catalytic domain-339-719 aa) by fluorescence based assay using 25 uM Ac-LRSR-AMC as substrate				J Med Chem 58: 8491-502 (2015) BindingDB Entry DOI: 10.7270/Q2PZ5BN1
					More data for this Ligand-Target Pair