BDBM50133452 5-[1-(4-Methoxy-benzenesulfonyl)-1,2,3,6-tetrahydro-pyridin-4-yl]-3-((R)-1-methyl-pyrrolidin-2-ylmethyl)-1H-indole::CHEMBL115941
SMILES: COc1ccc(cc1)S(=O)(=O)N1CCC(=CC1)c1ccc2[nH]cc(C[C@H]3CCCN3C)c2c1
InChI Key: InChIKey=DCJJVODWUIJFPH-JOCHJYFZSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 1D (Homo sapiens (Human)) | BDBM50133452 (5-[1-(4-Methoxy-benzenesulfonyl)-1,2,3,6-tetrahydr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 0.760 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Binding affinity towards cloned human 5-hydroxytryptamine 1D receptor | Bioorg Med Chem Lett 13: 3419-21 (2003) BindingDB Entry DOI: 10.7270/Q2PZ587T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1B (Homo sapiens (Human)) | BDBM50133452 (5-[1-(4-Methoxy-benzenesulfonyl)-1,2,3,6-tetrahydr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
NPS Pharmaceuticals Inc. Curated by ChEMBL | Assay Description Binding affinity towards cloned human 5-hydroxytryptamine 1B receptor | Bioorg Med Chem Lett 13: 3419-21 (2003) BindingDB Entry DOI: 10.7270/Q2PZ587T | |||||||||||
More data for this Ligand-Target Pair |