BDBM50133454 4-[3-((R)-1-Methyl-pyrrolidin-2-ylmethyl)-1H-indol-5-yl]-3,6-dihydro-2H-pyridine-1-carboxylic acid p-tolylamide::CHEMBL114571

SMILES: CN1CCC[C@@H]1Cc1c[nH]c2ccc(cc12)C1=CCN(CC1)C(=O)Nc1ccc(C)cc1

InChI Key: InChIKey=HLVNEWORWPHIMZ-XMMPIXPASA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50133454   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50133454 (4-[3-((R)-1-Methyl-pyrrolidin-2-ylmethyl)-1H-indol...) Show SMILES CN1CCC[C@@H]1Cc1c[nH]c2ccc(cc12)C1=CCN(CC1)C(=O)Nc1ccc(C)cc1 |t:19| Show InChI InChI=1S/C27H32N4O/c1-19-5-8-23(9-6-19)29-27(32)31-14-11-20(12-15-31)21-7-10-26-25(17-21)22(18-28-26)16-24-4-3-13-30(24)2/h5-11,17-18,24,28H,3-4,12-16H2,1-2H3,(H,29,32)/t24-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity towards cloned human 5-hydroxytryptamine 1D receptor				Bioorg Med Chem Lett 13: 3419-21 (2003) BindingDB Entry DOI: 10.7270/Q2PZ587T
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50133454 (4-[3-((R)-1-Methyl-pyrrolidin-2-ylmethyl)-1H-indol...) Show SMILES CN1CCC[C@@H]1Cc1c[nH]c2ccc(cc12)C1=CCN(CC1)C(=O)Nc1ccc(C)cc1 |t:19| Show InChI InChI=1S/C27H32N4O/c1-19-5-8-23(9-6-19)29-27(32)31-14-11-20(12-15-31)21-7-10-26-25(17-21)22(18-28-26)16-24-4-3-13-30(24)2/h5-11,17-18,24,28H,3-4,12-16H2,1-2H3,(H,29,32)/t24-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity towards cloned human 5-hydroxytryptamine 1B receptor				Bioorg Med Chem Lett 13: 3419-21 (2003) BindingDB Entry DOI: 10.7270/Q2PZ587T
					More data for this Ligand-Target Pair