BDBM50133458 4-[3-((R)-1-Methyl-pyrrolidin-2-ylmethyl)-1H-indol-5-yl]-3,6-dihydro-2H-pyridine-1-carbothioic acid phenylamide::CHEMBL334259

SMILES: CN1CCC[C@@H]1Cc1c[nH]c2ccc(cc12)C1=CCN(CC1)C(=S)Nc1ccccc1

InChI Key: InChIKey=KIZFBOUMJTUKDH-HSZRJFAPSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50133458   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50133458 (4-[3-((R)-1-Methyl-pyrrolidin-2-ylmethyl)-1H-indol...) Show SMILES CN1CCC[C@@H]1Cc1c[nH]c2ccc(cc12)C1=CCN(CC1)C(=S)Nc1ccccc1 |t:19| Show InChI InChI=1S/C26H30N4S/c1-29-13-5-8-23(29)16-21-18-27-25-10-9-20(17-24(21)25)19-11-14-30(15-12-19)26(31)28-22-6-3-2-4-7-22/h2-4,6-7,9-11,17-18,23,27H,5,8,12-16H2,1H3,(H,28,31)/t23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.680	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity towards cloned human 5-hydroxytryptamine 1D receptor				Bioorg Med Chem Lett 13: 3419-21 (2003) BindingDB Entry DOI: 10.7270/Q2PZ587T
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50133458 (4-[3-((R)-1-Methyl-pyrrolidin-2-ylmethyl)-1H-indol...) Show SMILES CN1CCC[C@@H]1Cc1c[nH]c2ccc(cc12)C1=CCN(CC1)C(=S)Nc1ccccc1 |t:19| Show InChI InChI=1S/C26H30N4S/c1-29-13-5-8-23(29)16-21-18-27-25-10-9-20(17-24(21)25)19-11-14-30(15-12-19)26(31)28-22-6-3-2-4-7-22/h2-4,6-7,9-11,17-18,23,27H,5,8,12-16H2,1H3,(H,28,31)/t23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NPS Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Binding affinity towards cloned human 5-hydroxytryptamine 1B receptor				Bioorg Med Chem Lett 13: 3419-21 (2003) BindingDB Entry DOI: 10.7270/Q2PZ587T
					More data for this Ligand-Target Pair