null

SMILES: C[C@H](CN1C2CCC1CC(Cc1ccc(Cl)cc1)C2)NC(=O)Nc1cccc(c1)S(C)(=O)=O

InChI Key: InChIKey=QDNRONLZDDMDPZ-UINAOQCUSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50133789   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50133789 (1-{(R)-2-[3-(4-Chloro-benzyl)-8-aza-bicyclo[3.2.1]...) Show SMILES C[C@H](CN1C2CCC1CC(Cc1ccc(Cl)cc1)C2)NC(=O)Nc1cccc(c1)S(C)(=O)=O |THB:10:9:3:5.6| Show InChI InChI=1S/C25H32ClN3O3S/c1-17(27-25(30)28-21-4-3-5-24(15-21)33(2,31)32)16-29-22-10-11-23(29)14-19(13-22)12-18-6-8-20(26)9-7-18/h3-9,15,17,19,22-23H,10-14,16H2,1-2H3,(H2,27,28,30)/t17-,19?,22?,23?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description Binding affinity was determined towards C-C chemokine receptor type 3 using [125I]-labeled eotaxin as radioligand				Bioorg Med Chem Lett 13: 3597-600 (2003) BindingDB Entry DOI: 10.7270/Q228085J
					More data for this Ligand-Target Pair
C-C chemokine receptor type 3 (Homo sapiens (Human))	BDBM50133789 (1-{(R)-2-[3-(4-Chloro-benzyl)-8-aza-bicyclo[3.2.1]...) Show SMILES C[C@H](CN1C2CCC1CC(Cc1ccc(Cl)cc1)C2)NC(=O)Nc1cccc(c1)S(C)(=O)=O |THB:10:9:3:5.6| Show InChI InChI=1S/C25H32ClN3O3S/c1-17(27-25(30)28-21-4-3-5-24(15-21)33(2,31)32)16-29-22-10-11-23(29)14-19(13-22)12-18-6-8-20(26)9-7-18/h3-9,15,17,19,22-23H,10-14,16H2,1-2H3,(H2,27,28,30)/t17-,19?,22?,23?/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Roche Palo Alto Curated by ChEMBL					Assay Description Compound was tested for its ability to inhibit C-C chemokine receptor type 3 receptor				Bioorg Med Chem Lett 13: 3597-600 (2003) BindingDB Entry DOI: 10.7270/Q228085J
					More data for this Ligand-Target Pair