BDBM50133845 5-[(Benzyl-methyl-amino)-methyl]-1-(2,6-difluoro-benzyl)-6-(4-dimethylamino-phenyl)-3-phenyl-1H-thieno[2,3-d]pyrimidine-2,4-dione::CHEMBL330835

SMILES: CN(Cc1c(sc2n(Cc3c(F)cccc3F)c(=O)n(-c3ccccc3)c(=O)c12)-c1ccc(cc1)N(C)C)Cc1ccccc1

InChI Key: InChIKey=LFBIGQYVSBGFCA-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50133845   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gonadotropin releasing hormone 1 (GnRHR1) (Homo sapiens (Human))	BDBM50133845 (5-[(Benzyl-methyl-amino)-methyl]-1-(2,6-difluoro-b...) Show SMILES CN(Cc1c(sc2n(Cc3c(F)cccc3F)c(=O)n(-c3ccccc3)c(=O)c12)-c1ccc(cc1)N(C)C)Cc1ccccc1 Show InChI InChI=1S/C36H32F2N4O2S/c1-39(2)26-19-17-25(18-20-26)33-29(22-40(3)21-24-11-6-4-7-12-24)32-34(43)42(27-13-8-5-9-14-27)36(44)41(35(32)45-33)23-28-30(37)15-10-16-31(28)38/h4-20H,21-23H2,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	61	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards human gonadotropin-releasing hormone receptor				Bioorg Med Chem Lett 13: 3617-22 (2003) BindingDB Entry DOI: 10.7270/Q24X576N
					More data for this Ligand-Target Pair