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SMILES: CN(Cc1c(sc2n(Cc3c(F)cccc3F)c(=O)n(-c3ccccc3)c(=O)c12)-c1ccc(NC(=O)CCCN)cc1)Cc1ccccc1

InChI Key: InChIKey=JVBJPLUJGOISDF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50133850   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gonadotropin-releasing hormone receptor


(Homo sapiens (Human))		BDBM50133850
PNG
(4-Amino-N-{4-[5-[(benzyl-methyl-amino)-methyl]-1-(...)
Show SMILES CN(Cc1c(sc2n(Cc3c(F)cccc3F)c(=O)n(-c3ccccc3)c(=O)c12)-c1ccc(NC(=O)CCCN)cc1)Cc1ccccc1
Show InChI InChI=1S/C38H35F2N5O3S/c1-43(22-25-10-4-2-5-11-25)23-30-34-36(47)45(28-12-6-3-7-13-28)38(48)44(24-29-31(39)14-8-15-32(29)40)37(34)49-35(30)26-17-19-27(20-18-26)42-33(46)16-9-21-41/h2-8,10-15,17-20H,9,16,21-24,41H2,1H3,(H,42,46)
PDB

KEGG

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PC cid
PC sid
UniChem

Similars
PubMed
 300n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards human gonadotropin-releasing hormone receptor

Bioorg Med Chem Lett 13: 3617-22 (2003)


BindingDB Entry DOI: 10.7270/Q24X576N
More data for this
Ligand-Target Pair