null

SMILES: CC(=O)N1CC[C@@H](NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)c2cc(CC3Cc4ccccc4C3)ccc12

InChI Key: InChIKey=SDHVKIPCPNNVQK-XZWHSSHBSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50133892   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50133892 (CHEMBL3634256) Show SMILES CC(=O)N1CC[C@@H](NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)c2cc(CC3Cc4ccccc4C3)ccc12 |r| Show InChI InChI=1S/C32H37N3O3/c1-19-12-26(37)13-20(2)27(19)18-29(33)32(38)34-30-10-11-35(21(3)36)31-9-8-22(17-28(30)31)14-23-15-24-6-4-5-7-25(24)16-23/h4-9,12-13,17,23,29-30,37H,10-11,14-16,18,33H2,1-3H3,(H,34,38)/t29-,30+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from rat mu-opioid receptor expressed in C6 cell membrane for 1 hr by liquid scintillation counting analysis				J Med Chem 58: 8952-69 (2015) BindingDB Entry DOI: 10.7270/Q2RR213J
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Rattus norvegicus (rat))	BDBM50133892 (CHEMBL3634256) Show SMILES CC(=O)N1CC[C@@H](NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)c2cc(CC3Cc4ccccc4C3)ccc12 |r| Show InChI InChI=1S/C32H37N3O3/c1-19-12-26(37)13-20(2)27(19)18-29(33)32(38)34-30-10-11-35(21(3)36)31-9-8-22(17-28(30)31)14-23-15-24-6-4-5-7-25(24)16-23/h4-9,12-13,17,23,29-30,37H,10-11,14-16,18,33H2,1-3H3,(H,34,38)/t29-,30+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from rat delta-opioid receptor expressed in C6 cell membrane for 1 hr by liquid scintillation counting analysis				J Med Chem 58: 8952-69 (2015) BindingDB Entry DOI: 10.7270/Q2RR213J
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50133892 (CHEMBL3634256) Show SMILES CC(=O)N1CC[C@@H](NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)c2cc(CC3Cc4ccccc4C3)ccc12 |r| Show InChI InChI=1S/C32H37N3O3/c1-19-12-26(37)13-20(2)27(19)18-29(33)32(38)34-30-10-11-35(21(3)36)31-9-8-22(17-28(30)31)14-23-15-24-6-4-5-7-25(24)16-23/h4-9,12-13,17,23,29-30,37H,10-11,14-16,18,33H2,1-3H3,(H,34,38)/t29-,30+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphine from human kappa-opioid receptor expressed in CHO cell membrane for 1 hr by liquid scintillation counting analysis				J Med Chem 58: 8952-69 (2015) BindingDB Entry DOI: 10.7270/Q2RR213J
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50133892 (CHEMBL3634256) Show SMILES CC(=O)N1CC[C@@H](NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)c2cc(CC3Cc4ccccc4C3)ccc12 |r| Show InChI InChI=1S/C32H37N3O3/c1-19-12-26(37)13-20(2)27(19)18-29(33)32(38)34-30-10-11-35(21(3)36)31-9-8-22(17-28(30)31)14-23-15-24-6-4-5-7-25(24)16-23/h4-9,12-13,17,23,29-30,37H,10-11,14-16,18,33H2,1-3H3,(H,34,38)/t29-,30+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	610	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Agonist activity at human kappa-opioid receptor expressed in CHO cell membrane assessed as [35S]GTPgammaS binding for 1 hr by liquid scintillation co...				J Med Chem 58: 8952-69 (2015) BindingDB Entry DOI: 10.7270/Q2RR213J
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50133892 (CHEMBL3634256) Show SMILES CC(=O)N1CC[C@@H](NC(=O)[C@@H](N)Cc2c(C)cc(O)cc2C)c2cc(CC3Cc4ccccc4C3)ccc12 |r| Show InChI InChI=1S/C32H37N3O3/c1-19-12-26(37)13-20(2)27(19)18-29(33)32(38)34-30-10-11-35(21(3)36)31-9-8-22(17-28(30)31)14-23-15-24-6-4-5-7-25(24)16-23/h4-9,12-13,17,23,29-30,37H,10-11,14-16,18,33H2,1-3H3,(H,34,38)/t29-,30+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	0.560	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Agonist activity at rat mu-opioid receptor expressed in C6 cell membrane assessed as [35S]GTPgammaS binding for 1 hr by liquid scintillation counting...				J Med Chem 58: 8952-69 (2015) BindingDB Entry DOI: 10.7270/Q2RR213J
					More data for this Ligand-Target Pair