BDBM50134105 (3aR,10R)-10-(4-Methoxy-phenyl)-2-methyl-3a,4,9,10-tetrahydro-2,9,10a-triaza-cyclopenta[b]fluorene-1,3-dione::CHEMBL344173

SMILES: COc1ccc(cc1)[C@@H]1c2[nH]c3ccccc3c2Cc2c(O)n(C)c(=O)n12

InChI Key: InChIKey=XOPAODYMIVJJNI-LJQANCHMSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50134105   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 5A (Bos taurus)	BDBM50134105 ((3aR,10R)-10-(4-Methoxy-phenyl)-2-methyl-3a,4,9,10...) Show SMILES COc1ccc(cc1)[C@@H]1c2[nH]c3ccccc3c2Cc2c(O)n(C)c(=O)n12 Show InChI InChI=1S/C21H19N3O3/c1-23-20(25)17-11-15-14-5-3-4-6-16(14)22-18(15)19(24(17)21(23)26)12-7-9-13(27-2)10-8-12/h3-10,19,22,25H,11H2,1-2H3/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description Inhibitory activity against bovine PDE5 (phosphodiesterase-5).				J Med Chem 46: 4525-32 (2003) Article DOI: 10.1021/jm030056e BindingDB Entry DOI: 10.7270/Q2NP255G
					More data for this Ligand-Target Pair